Rosenthal, Victor Daniel and Yin, Ruijie and Lu, Yawen and Rodrigues, Camilla and Myatraa, Sheila Nainan and Kharbanda, Mohit and Valderrama-Beltran, Sandra Liliana and Mehta, Yatin and Daboor, Mohammad Abdellatif and Todi, Subhash Kumar and Aguirre-Avalos, Guadalupe and Guclu, Ertugrul and Gan, Chin Seng and Jimenez-Alvarez, Luisa Fernanda and Chawla, Rajesh and Hlinkova, Sona and Arjun, Rajalakshmi and Agha, Hala Mounir and Zuniga-Chavarria, Maria Adelia and Davaadagva, Narangarav and Basri, Mat Nor Mohd and Gomez-Nieto, Katherine and Aguilar-de-Moros, Daisy and Tai, Chian-Wern Tai and Sassoe-Gonzalez, Alejandro and Aguilar-Moreno, Lina Alejandra and Sandhu, Kavita and Janc, Jaroslaw and Aleman-Bocanegra, Mary Cruz and Yildizdas, Dincer and Cano-Medina, Yuliana Andrea and Villegas-Mota, Maria Isabel and Omar, Abeer Aly and Duszynska, Wieslawa and BelKebir, Souad and El-Kholy, Amani Ali and Alkhawaja, Safaa Abdulaziz and Florin, George Horhat and Medeiros, Eduardo Alexandrino and Tao, Lili Tao and Mimish, Ziad A. and Jin, Zhilin Jin (2023) The impact of healthcare-associated infections on mortality in ICU: A prospective study in Asia, Africa, Eastern Europe, Latin America, and the Middle East. American Journal of Infection Control, 51 (6). pp. 675-682. ISSN 0196-6553, DOI https://doi.org/10.1016/j.ajic.2022.08.024.
Full text not available from this repository.Abstract
Background: The International Nosocomial Infection Control Consortium has found a high ICU mortality rate. Our aim was to identify all-cause mortality risk factors in ICU-patients. Methods: Multinational, multicenter, prospective cohort study at 786 ICUs of 312 hospitals in 147 cities in 37 Latin American, Asian, African, Middle Eastern, and European countries. Results: Between 07/01/1998 and 02/12/2022, 300,827 patients, followed during 2,167,397 patient-days, acquired 21,371 HAIs. Following mortality risk factors were identified in multiple logistic regression: Central line-associated bloodstream infection (aOR:1.84; P<.0001); ventilator-associated pneumonia (aOR:1.48; P<.0001); catheter-associated urinary tract infection (aOR:1.18;P<.0001); medical hospitalization (aOR:1.81; P<.0001); length of stay (LOS), risk rises 1% per day (aOR:1.01; P<.0001); female gender (aOR:1.09; P<.0001); age (aOR:1.012; P<.0001); central line-days, risk rises 2% per day (aOR:1.02; P<.0001); and mechanical venti-lator (MV)-utilization ratio (aOR:10.46; P<.0001). Coronary ICU showed the lowest risk for mortality (aOR: 0.34;P<.0001). Conclusion: Some identified risk factors are unlikely to change, such as country income-level, facility owner-ship, hospitalization type, gender, and age. Some can be modified; Central line-associated bloodstream infec-tion, ventilator-associated pneumonia, catheter-associated urinary tract infection, LOS, and MV-utilization. So, to lower the risk of death in ICUs, we recommend focusing on strategies to shorten the LOS, reduce MV -utilization, and use evidence-based recommendations to prevent HAIs. (c) 2022 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Funders: | INICC Advi-sory Board |
| Uncontrolled Keywords: | Risk factor; Risk factor Hospital infections; Hospital Nosocomial infections; Nosocomial infections Intensive care unit; Intensive care Worldwide; Multiple Logistic Regression |
| Subjects: | R Medicine > RA Public aspects of medicine |
| Divisions: | Universiti Malaya Medical Centre (UMMC) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 28 Jul 2025 04:36 |
| Last Modified: | 28 Jul 2025 04:36 |
| URI: | http://eprints.um.edu.my/id/eprint/50783 |
Actions (login required)
 |
View Item |
