Tang, Sin-Yee and Tan, Chun-Hoe and Sim, Kae-Shin and Yong, Kien-Thai and Lim, Kuan-Hon and Low, Yun-Yee and Lim, Siew-Huah (2023) Polyneurines A-H, iboga alkaloids from Tabernaemontana polyneura. Phytochemistry, 208. ISSN 0031-9422, DOI https://doi.org/10.1016/j.phytochem.2023.113587.
Full text not available from this repository.Abstract
Eight undescribed iboga alkaloids, polyneurines A-H, were isolated from the bark of Tabernaemontana polyneura. The structures of these alkaloids were established by interpretation of the MS and NMR data, while the con-figurations were determined using GIAO NMR calculations and DP4+ probability analysis, TDDFT-ECD method, or X-ray diffraction analysis. Polyneurine A possesses a y-lactone unit embedded within the iboga skeleton, while polyneurines D and E incorporate a formylmethyl moiety at C-3 of the iboga skeleton. Biosynthetic pathways towards the formation of polyneurines A, C, D, and E were proposed.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya and MOHE Malaysia (FRGS/1/2019/STG01/UM/02/23) |
| Uncontrolled Keywords: | Tabernaemontana polyneura; Apocynaceae; Iboga; Alkaloids; ECD; DP4+; X-ray diffraction |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry Q Science > QH Natural history |
| Divisions: | Faculty of Science > Institute of Biological Sciences Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 18 Sep 2025 06:46 |
| Last Modified: | 18 Sep 2025 06:46 |
| URI: | http://eprints.um.edu.my/id/eprint/50432 |
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