Howell, Jessica and Seaman, Chris and Wallace, Jack and Xiao, Yinzong and Scott, Nick and Davies, Jane and de Santis, Teresa and Adda, Danjuma and El-Sayed, Manal and Feld, Jordan J. and Gane, Edward and Lacombe, Karine and Lesi, Olufunmilayo and Mohamed, Rosmawati and Silva, Marcelo and Tu, Thomas and Revill, Peter and Hellard, Margaret E. (2023) Pathway to global elimination of hepatitis B: HBV cure is just the first step. Hepatology, 78 (3). pp. 976-990. ISSN 0270-9139, DOI https://doi.org/10.1097/HEP.0000000000000430.
Full text not available from this repository.Abstract
Hepatitis B (HBV) is a major cause of global morbidity and mortality, and the leading cause of liver cancer worldwide. Significant advances have recently been made toward the development of a finite HBV treatment that achieves permanent loss of HBsAg and HBV DNA (so-called ``HBV cure''), which could provide the means to eliminate HBV as a public health threat. However, the HBV cure is just one step toward achieving WHO HBV elimination targets by 2030, and much work must be done now to prepare for the successful implementation of the HBV cure. In this review, we describe the required steps to rapidly scale-up future HBV cure equitably. We present key actions required for successful HBV cure implementation, integrated within the World Health Organization (WHO) Global Health Sector Strategy (GHSS) 2022-2030 framework. Finally, we highlight what can be done now to progress toward the 2030 HBV elimination targets using available tools to ensure that we are preparing, but not waiting, for the cure.
| Item Type: | Article |
|---|---|
| Funders: | World Health Organization (001) |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 23 Oct 2025 06:32 |
| Last Modified: | 23 Oct 2025 06:32 |
| URI: | http://eprints.um.edu.my/id/eprint/50165 |
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