Fornace, Kimberly M. and Laporta, Gabriel Zorello and Vythilingham, Indra and Chua, Trock Hing and Chua, rock Hing and Ahmed, Kamruddin and Jeyaprakasam, Nantha K. and Duarte, Ana Maria Ribeiro de Castro and Amir, Amirah and Phang, Wei Kit and Drakeley, Chris and Sallum, Maria Anice M. and Lau, Yee Ling (2023) Simian malaria: a narrative review on emergence, epidemiology andthreatto global malaria elimination. Lancet Infectious Diseases, 23 (12). E520-E532. ISSN 1473-3099, DOI https://doi.org/10.1016/S1473-3099(23)00298-0.
Full text not available from this repository.Abstract
Simian malaria from wild non-human primate populations is increasingly recognised as a public health threat and is now the main cause of human malaria in Malaysia and some regions of Brazil. In 2022, WHO changed malaria elimination certification guidelines to require non-negligible risks of simian malaria in people, leaving many countries with no pathway to elimination. We review the global distribution and drivers of simian malaria and identify priorities for diagnosis, treatment, surveillance, and control. Environmental change is driving closer interactions between humans and wildlife, with malaria parasites from non-human primates spilling over into human populations and human malaria parasites spilling back into wild non-human primate populations. These complex transmission cycles require new molecular and epidemiological approaches to track parasite spread. Current methods of malaria control are ineffective, with wildlife reservoirs and primarily outdoor-biting mosquito vectors urgently requiring the development of novel control strategies. Without these, simian malaria has the potential to undermine malaria elimination globally.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Parasitology Deparment |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 23 Oct 2025 07:48 |
| Last Modified: | 23 Oct 2025 07:48 |
| URI: | http://eprints.um.edu.my/id/eprint/50101 |
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