Chin, Kim-Ling and Tan, Kim-Kee and Abu Bakar, Sazaly and Zainal, Nurhafiza (2023) Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review. Asian Pacific Journal of Tropical Medicine, 16 (12). pp. 546-557. ISSN 1995-7645, DOI https://doi.org/10.4103/1995-7645.391776.
Full text not available from this repository.Abstract
Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological manifestations. Flavivirus infections cause a substantial global health impact, with an estimated more than 400 million cases of infections annually. Hence, an understanding of flavivirus-host interaction is urgently needed for new antiviral therapeutic strategies. In recent years, many aspects concerning epigenetic therapy for viral infections have been addressed, including methylation of the genome, acetylation/deacetylation of histone complex and microRNA regulation. In this context, we surveyed and reviewed the literature and summarized the epigenetic effects of resveratrol, a natural polyphenol with potential anti-viral properties, on flavivirus infections.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Faculty of Medicine > Medical Microbiology Department Institute of Advanced Studies Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 28 Oct 2025 08:23 |
| Last Modified: | 28 Oct 2025 08:23 |
| URI: | http://eprints.um.edu.my/id/eprint/50085 |
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