Overcoming Therapeutic Inertia as the Achilles' Heel for Improving Suboptimal Diabetes Care: An Integrative Review

Chew, Boon-How and Mohd-Yusof, Barakatun-Nisak and Lai, Pauline Siew Mei and Khunti, Kamlesh (2023) Overcoming Therapeutic Inertia as the Achilles' Heel for Improving Suboptimal Diabetes Care: An Integrative Review. Endocrinology and Metabolism, 38 (1). pp. 34-42. ISSN 2093-596X, DOI https://doi.org/10.3803/EnM.2022.1649.

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Abstract

The ultimate purpose of diabetes care is achieving the outcomes that patients regard as important throughout the life course. Despite advances in pharmaceuticals, nutraceuticals, psychoeducational programs, information technologies, and digital health, the levels of treatment target achievement in people with diabetes mellitus (DM) have remained suboptimal. This clinical care of people with DM is highly challenging, complex, costly, and confounded for patients, physicians, and healthcare systems. One key underlying prob-lem is clinical inertia in general and therapeutic inertia (TI) in particular. TI refers to healthcare providers' failure to modify therapy appropriately when treatment goals are not met. TI therefore relates to the prescribing decisions made by healthcare professionals, such as doctors, nurses, and pharmacists. The known causes of TI include factors at the level of the physician (50%), patient (30%), and health system (20%). Although TI is often multifactorial, the literature suggests that 28% of strategies are targeted at multiple levels of causes, 38% at the patient level, 26% at the healthcare professional level, and only 8% at the healthcare system level. The most effective interventions against TI are shorter intervals until revisit appointments and empowering nurses, diabetes educators, and pharmacists to review treatments and modify prescriptions.

Item Type: Article
Funders: National Institute for Health Research (NIHR) Applied Research Collaboration East Midlands (ARC EM), NIHR Leicester Biomedical Research Centre (BRC)
Uncontrolled Keywords: Diabetes mellitus; Therapeutics; Medication adherence
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Primary Care Medicine Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 30 Oct 2025 09:00
Last Modified: 30 Oct 2025 09:00
URI: http://eprints.um.edu.my/id/eprint/49916

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