Nasution, Dewi L. I. and Furuta, Michiko and Li, Huihua and Zakaria, Myrna Nurlatifah and Takeshita, Toru and Peres, Marco A. and Yamashita, Yoshihisa (2023) Longitudinal association between periodontal condition and glycaemic status in middle-aged adults: A cross-lagged panel analysis. Journal of Clinical Periodontology, 50 (8). pp. 1042-1050. ISSN 0303-6979, DOI https://doi.org/10.1111/jcpe.13809.
Full text not available from this repository.Abstract
Aim To investigate the existence of a bidirectional temporal relationship between periodontal condition and glycaemic status. Materials and Methods This longitudinal study included 2198 participants with mean age 43.4 +/- 7.7 years, who underwent dental examinations in Yokohama, Japan, at two time points, 2003-2004 and 2008-2009, at an interval of 5 years. Periodontal condition was assessed by the mean value of probing pocket depth (PPD) and clinical attachment level (CAL). Glycaemic status was assessed by fasting glucose and glycated haemoglobin (HbA1c). Results The cross-lagged panel models showed the effect of HbA1c at baseline on mean PPD at follow-up (beta = 0.044, p = .039). There was a marginal effect of fasting glucose on the mean PPD (beta = 0.037, p = .059). It was similar to the effect of fasting glucose or HbAlc on mean CAL. However, in the opposite direction, no effect of mean PPD or CAL at baseline on fasting glucose or HbAlc at follow-up was identified. Conclusions This study demonstrated a unidirectional relationship between glycaemic status and periodontal condition. The study population, however, had mostly mild periodontitis. Future studies are needed to investigate the effect of periodontal condition on glycaemic status in patients with severe periodontitis.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | blood glucose; glycated haemoglobin A; oral health; periodontitis |
| Subjects: | R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry > Department of Restorative Dentistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 03 Nov 2025 08:32 |
| Last Modified: | 03 Nov 2025 08:32 |
| URI: | http://eprints.um.edu.my/id/eprint/49850 |
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