Clinicopathological correlation of oral candidiasis: Our experience in a tertiary centre over two decades

Tan, Chuey Chuan and Lim, Daniel and Mohd Hisham, Nurin Qistina and Elias, Noralia Auni and Azli, Anis Syahirah and Goh, Yet Ching (2023) Clinicopathological correlation of oral candidiasis: Our experience in a tertiary centre over two decades. Malaysian Journal of Pathology, 45 (2). pp. 237-246. ISSN 0126-8635,

Full text not available from this repository.

Abstract

Introduction: Oral candidiasis is one of the most common fungal infections that has been widely reported around the world. In Malaysia, the available studies for this infection are scarce. Materials and Methods: This is a 20-year retrospective study aimed to investigate the prevalence, demographic characteristics, clinical presentations, and the association of oral candidiasis with clinical parameters in oral candidiasis cases reported in the Faculty of Dentistry, Universiti Malaya from 1999 until 2019. A total of 12,964 histopathological records from the Oral Pathology Diagnostic and Research Laboratory (OPDRL) between 1999 to 2019 were retrieved. Oral candidiasis cases were selected according to the inclusion and exclusion criteria. Information of interest was obtained and analysed. Results: From the total records retrieved, 378 oral candidiasis cases were recorded and 82.8% were diagnosed from smear test. This study showed that oral candidiasis was predominantly reported in female (64.2%) and Indian population (64.2%). The peak incidence was in the sixth decades of life (27.0%). The most commonly affected site was tongue and coated tongue was the most common clinical presentation. More than 50% of the cases had comorbidity and 10.6% were associated with dentures. Ethnicity and site of occurrence were significantly associated (p<0.05) with oral candidiasis. Conclusion: This is the first large-scale study of oral candidiasis cases in Malaysia. The findings of this study are useful for clinical assessment of patients suspected of oral candidiasis.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Demography; Malaysia; oral candidiasis; prevalence
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Department of Oral & Maxillofacial Clinical Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 31 Oct 2025 01:03
Last Modified: 31 Oct 2025 01:03
URI: http://eprints.um.edu.my/id/eprint/48678

Actions (login required)

View Item View Item