Rosli, Muhammad Zahin and Mohd-Taib, Farah Shafawati and Khoo, Jing Jing and Chee, Hui Yee and Wong, Yien Ping and Shafie, Nur Juliani and Mohamed, Nor Zalipah and AbuBakar, Sazaly and Md Nor, Shukor (2023) A Multi-landscape assessment of leptospira prevalence on a diversity of small mammals. Ecohealth, 20 (2). pp. 208-224. ISSN 1612-9202, DOI https://doi.org/10.1007/s10393-023-01637-8.
Full text not available from this repository.Abstract
Leptospirosis is a major zoonotic disease, especially in the tropics, and rodents were known to be carriers of this bacterium. There was established information on Leptospira prevalence among animal reservoirs in human-dominated landscapes from previous literature. However, there was very little focus given comparing the prevalence of Leptospira in a wide range of habitats. An extensive sampling of small mammals from various landscapes was carried out, covering oil palm plantations, paddy fields, recreational forests, semi-urbans, and wet markets in Peninsular Malaysia. This study aims to determine the prevalence of pathogenic Leptospira in a diversity of small mammals across different landscapes. Cage-trapping was deployed for small mammals' trappings, and the kidneys of captured individuals were extracted, for screening of pathogenic Leptospira by polymerase chain reaction (PCR) using LipL32 primer. Eight microhabitat parameters were measured at each study site. Out of 357 individuals captured, 21 (5.9%) were positive for pathogenic Leptospira of which recreational forest had the highest prevalence (8.8%) for landscape types, whereas Sundamys muelleri shows the highest prevalence (50%) among small mammals' species. Microhabitat analysis reveals that rubbish quantity (p < 0.05) significantly influenced the Leptospira prevalence among small mammals. Furthermore, nMDS analysis indicates that the presence of faeces, food waste, and exposure to humans in each landscape type also were linked with high prevalence of pathogenic Leptospira among the small mammals. This study supplements previous studies on pathogenic Leptospira prevalence across different landscape types, and the major microhabitat factors associated with Leptospira prevalence. This information is crucial for epidemiological surveillance and habitat management to curb the possibility of the disease outbreaks.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Higher Education of Malaysia through Fundamental Research Grant Scheme [Grant No: FRGS/1/2018/STG03/UKM/02/1], Ministry of Higher Education of Malaysia through Prototype Development Research Grant Scheme [Grant No: PRGS/1/2019/SKK11/UPM/02/2], Newton-Ungku Omar Fund partnership [Grant No: 332192305], UK Department of Business, Energy, and Industrial Strategy (BEIS), UK Department of Energy and Industrial Strategy, Malaysian Industry-Government Group for High Technology (MIGHT), Ministry of Education, Malaysia under the Higher Institution Centre of Excellence (HICoE) program [Grant No: MO002-2019] |
| Uncontrolled Keywords: | Rodents; Pathogenic; Leptospira; Prevalence; Microhabitat; Wet market; Agriculture |
| Subjects: | G Geography. Anthropology. Recreation > GE Environmental Sciences |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 06 Oct 2025 04:44 |
| Last Modified: | 06 Oct 2025 04:44 |
| URI: | http://eprints.um.edu.my/id/eprint/48307 |
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