Cerebral venous sinus thrombosis in young children with inflammatory bowel disease: A report of two cases

Ranai, Norashikin Mohd and Chew, Kee Seang and Lim, Wei Kang and Fong, Choong Yi and Li, Limin and Ng, Ruey Terng and Lee, Way Seah (2023) Cerebral venous sinus thrombosis in young children with inflammatory bowel disease: A report of two cases. Neurology Asia, 28 (3). pp. 781-783. ISSN 1823-6138, DOI kschew@ummc.edu.my.

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Abstract

We describe two young children aged 2 and 5-year-old with very early onset inflammatory bowel disease (IBD), who developed focal seizures during an acute flare of disease. Cerebral venous sinus thrombosis (CVST) was confirmed with magnetic resonance imaging and magnetic resonance venography of the brain. CVST is a rare complication of paediatric IBD that can cause significant morbidity and mortality. The important risk factor for CVST in our children was active disease, which exposed them to an increased prothrombic state. Aggressive treatment of IBD resulted in full neurological recovery of our patients and resolution of the CVST. Our case report is the youngest reported age of CVST associated with IBD to date and highlights the need for clinicians to be vigilant for this rare complication, even in young children with IBD.

Item Type: Article
Funders: None
Uncontrolled Keywords: Cerebral venous sinus thrombosis (CVST); inflammatory bowel disease (IBD); venous; thromboembolism (VTE); children
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 11 Oct 2025 12:51
Last Modified: 11 Oct 2025 12:51
URI: http://eprints.um.edu.my/id/eprint/48161

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