Djukelic, Mario and Martin, Colin John and Abuhaimed, Abdullah and Kron, Tomas and Gros, Sebastien and Wood, Tim and Pankowski, Piotr and Ung, Ngie Min and Vassileva, Jenia and Plazas, Maria Cristina and Vostinic, Snezana and Lazovic, Anja and Sa, Ana Cravo and Nilsson, Isabelle and Koutrouli, Marianna and Murugan, Lavanya and Fourie, Hein and Miadzvetski, Aliaksandr and Al Ameri, Buthaina and Dumancic, Mirta and Cheung, Anson Ho-Yin and Al Rahbi, Zakiya and Roussakis, Yiannis and Shaaban, Hossam Ragab and Liang, Runcheng and Tomic, Nada and Correa, Daniel Eduardo Salazar and Butler, Duncan and Small Jr, William (2025) Cone beam CT (CBCT) in radiotherapy: Assessment of doses using a pragmatic setup in an international setting. Physica Medica-European Journal of Medical Physics, 131. p. 104937. ISSN 1120-1797, DOI https://doi.org/10.1016/j.ejmp.2025.104937.
Full text not available from this repository.Abstract
Introduction: The imaging modality kV CBCT on linear accelerators (linacs) is utilised to verify positioning and anatomy in cancer patients undergoing radiotherapy treatment. There is a need for optimisation of radiological protection in kV CBCT imaging protocols to avoid unnecessarily high exposures to normal tissues surrounding the target. Methods: A network of ICRP mentees from 23 countries were surveyed for available dosimetry equipment. Standardised measurements on CBCT linac imaging systems were conducted using a cone beam dose index (CBDI) devised as a straightforward measurement for wide beam doses. Measurements were made with (a) 100 mm ionisation chambers or (b) 0.6 cc Farmer ionisation chambers and cylindrical CT PMMA phantoms, and (c) an alternative setup of Farmer chambers and cubical phantoms comprised of slabs of water equivalent material readily available in radiotherapy centres. The measurements were compared with Monte Carlo (MC) simulations. Results: The survey showed limited availability for the reference setup using 100 mm chambers and CT phantoms. Correction factors were derived to convert normalised CBDI from alternative setups to the reference setup and are on average within 2% of MC simulations. Conclusion: The slab phantom in combination with a Farmer chamber provides an alternative to quantify CBCT radiation dose indices from linac-based image-guided radiotherapy using materials accessible in most centres worldwide. A method is presented to use correction factors for Varian Truebeam linacs if traditional 100 mm chambers and cylindrical CT phantoms are not available. This will enable most radiotherapy centres across the world to engage in meaningful imaging dose measurement and optimisation.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Image-guided radiotherapy; kV cone beam computed tomography; Cone beam dose index; Water equivalent phantom; On-board imager; Dosimetry; Farmer ionisation chamber; Correction factor |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 05 May 2025 07:27 |
| Last Modified: | 05 May 2025 07:27 |
| URI: | http://eprints.um.edu.my/id/eprint/47861 |
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