Fatemi, Kiyana and Lau, Sie Yon and Obayomi, Kehinde Shola and Kiew, Siaw Fui and Coorey, Ranil and Chung, Lip Yong and Fatemi, Reza and Heshmatipour, Zoheir and Premarathna, K. S. D. (2024) Carbon nanomaterial-based aptasensors for rapid detection of foodborne pathogenic bacteria. Analytical Biochemistry, 695. p. 115639. ISSN 0003-2697, DOI https://doi.org/10.1016/j.ab.2024.115639.
Full text not available from this repository.Abstract
Each year, millions of people suffer from foodborne illness due to the consumption of food contaminated with pathogenic bacteria, which severely challenges global health. Therefore, it is essential to recognize foodborne pathogens swiftly and correctly. However, conventional detection techniques for bacterial pathogens are laborintensive, low selectivity, and time-consuming, highlighting a notable knowledge gap. A novel approach, aptamer-based biosensors (aptasensors) linked to carbon nanomaterials (CNs), has shown the potential to overcome these limitations and provide a more reliable method for detecting bacterial pathogens. Aptamers, short single-stranded DNA (ssDNA)/RNA molecules, serve as bio-recognition elements (BRE) due to their exceptionally high affinity and specificity in identifying foodborne pathogens such as Salmonella spp., Escherichia coli (E. coli), Listeria monocytogenes, Campylobacter jejuni, and other relevant pathogens commonly associated with foodborne illnesses. Carbon nanomaterials' high surface area-to-volume ratio contributes unique characteristics crucial for bacterial sensing, as it improves the binding capacity and signal amplification in the design of aptasensors. Furthermore, aptamers can bind to CNs and create aptasensors with improved signal specificity and sensitivity. Hence, this review intends to critically review the current literature on developing aptamer functionalized CN-based biosensors by transducer optical and electrochemical for detecting foodborne pathogens and explore the advantages and challenges associated with these biosensors. Aptasensors conjugated with CNs offers an efficient tool for identifying foodborne pathogenic bacteria that is both precise and sensitive to potentially replacing complex current techniques that are time-consuming.
| Item Type: | Article |
|---|---|
| Funders: | Yayasan Sarawak Development, Curtin University, Malaysia's Curtin Malaysia Postgraduate Research Scholarship (CMPRS) |
| Uncontrolled Keywords: | Carbon nanomaterials; Food safety; Aptasensors; Optical; Electrochemical; Bacteria detection |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmaceutical Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 06 Feb 2025 05:12 |
| Last Modified: | 06 Feb 2025 05:12 |
| URI: | http://eprints.um.edu.my/id/eprint/47530 |
Actions (login required)
 |
View Item |
