Dimitri, Paul and van Dommelen, Paula and Banerjee, Indraneel and Bellazzi, Riccardo and Ciaccio, Marta and Munoz, Antonio de Arriba and Loche, Sandro and Zaini, Azriyanti Anuar and Halabi, Ammar and Bagha, Merat and Koledova, Ekaterina (2024) Opportunities for digitally-enabled personalization and decision support for pediatric growth hormone therapy. Frontiers in Endocrinology, 15. p. 1436778. ISSN 1664-2392, DOI https://doi.org/10.3389/fendo.2024.1436778.
Full text not available from this repository.Abstract
Smart technologies and connected health are providing opportunities for improved healthcare for chronic conditions. Acceptance by healthcare professionals (HCPs) and patients is crucial for successful implementation. Evidence-based standards, technological infrastructure and regulatory processes are needed to integrate digital tools into clinical practice. Personal health records provide continuity and aid decision-making, while machine-learning algorithms may help in optimizing therapies and improving outcomes. Digital healthcare can negate geographical barriers, enabling patients in remote areas to access specialist endocrine expertise. We review available and developing digital tools to manage care for patients requiring growth hormone (GH) therapy for growth failure conditions. GH is most often administered via daily injections over several years; continuous adherence is necessary but may become insufficient. Future development and integration of electronic platforms for GH therapy requires involvement of all stakeholders in design-thinking approaches and human-factor testing. Growzen Connect is an innovative digital ecosystem designed to increase the management and monitoring of GH therapy, comprising the easypod device and connected mobile apps. It provides a real-time overview of a patient's therapy, including adherence and growth response, which aids decision-making by HCPs and empowers patients to engage in their therapy journey. Incorporating prediction models for adherence and growth in the ecosystem helps patients build treatment habits and allows issues to be addressed in a timely fashion. A connected ecosystem for GH therapy can enhance outcomes and empower patients, fostering a collaborative and patient-centered approach that is more proactive, beyond the traditional clinic-based approach.
| Item Type: | Article |
|---|---|
| Funders: | Merck & Company (10.13039/100009945) |
| Uncontrolled Keywords: | decision support; digital; growth hormone; pediatric; technology |
| Subjects: | R Medicine > RJ Pediatrics |
| Divisions: | Faculty of Medicine > Paediatrics Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 17 Feb 2025 01:02 |
| Last Modified: | 17 Feb 2025 01:02 |
| URI: | http://eprints.um.edu.my/id/eprint/47421 |
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