Hashim, Nurul Nabilah Akmal and Mat, Sumaiyah and Myint, Phyo Kyaw and Kioh, Sheng Hui and Delibegovic, Mirela and Chin, Ai-Vyrn and Kamaruzzaman, Shahrul Bahyah and Hairi, Noran Naqiah and Khoo, Selina Phaik Kin and Tan, Maw Pin (2024) Association between weight and body composition changes with falls risk in the Malaysian Elders Longitudinal Research (MELoR) study. BMJ Open, 14 (11). e087358. ISSN 2044-6055, DOI https://doi.org/10.1136/bmjopen-2024-087358.
Full text not available from this repository.Abstract
Objective Both changes in body composition and increased fall risk occur with increasing age. While weight management may be considered a component of falls prevention, the long-term consequences of changes in weight, however, remain uncertain. This prospective study aimed to evaluate the relationship between weight and body composition changes over 5 years with fall occurrence.Design Prospective cohort study.Setting Community-dwelling older adults interviewed at baseline (2013-2016) and follow-up (2020-2022) as a part of the Malaysian Elders Longitudinal Research study were included.Participants Participants who attended face-to-face follow-up visits.Primary and secondary outcome measures Fall occurrence over 12 months preceding the follow-up visit was determined. Anthropometric, bioimpedance analysis and physical performance measurements were obtained at both time points. Participants were categorised into three groups according to changes in weight and body composition using >= 5% increase or decrease in weight to determine loss or gain.Results Of the 225 participants, aged 71.8 +/- 6.8 years, 128 (56.9%) were women. Weight gain was associated with increased fall risk at follow-up compared with stable weight (adjusted rate ratio, aRR (95% confidence interval, CI)=2.86 (1.02-8.02)) following adjustments for age and body mass index (BMI), but this relationship was attenuated by low baseline percentage lean body mass (%LBM) in women. The association was strenghtened after adjusting for age, BMI, and low muscle strength (aRR (95% CI)=2.89 (1.01-8.28)). Weight change did not influence falls risk in men. No difference was observed with changes in percentage body fat and %LBM over time with fall occurrence for both genders.Conclusion Lower baseline lean body mass influenced the relationship between weight gain and falls longitudinally. Interventions addressing low lean body mass should be considered in the prevention of weight-gain-related falls in older women.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Education, Malaysia, Long-Term Research Grant Scheme (LRGS/1/2019/UM/01/1), Fundamental Research Grant Scheme (FRGS/1/2019/SKK02/UM/01/1) |
| Uncontrolled Keywords: | Weight Gain; Aging; Risk Factors |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Medicine Department Faculty of Medicine > Social & Preventive Medicine Faculty of Sports and Exercise Science (formerly known as Centre for Sports & Exercise Sciences) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 21 Feb 2025 03:11 |
| Last Modified: | 21 Feb 2025 03:11 |
| URI: | http://eprints.um.edu.my/id/eprint/47337 |
Actions (login required)
 |
View Item |
