Chemical constituents from Cyathostemma wrayi king and their chemophenetic significance

Sulaiman, Syazreen Nadia and Othman, Muhamad Aqmal and Din, Mohd Fadzli Md and Awang, Khalijah and Zahari, Azeana and Liew, Sook Yee (2024) Chemical constituents from Cyathostemma wrayi king and their chemophenetic significance. Biochemical Systematics and Ecology, 117. p. 104916. ISSN 0305-1978, DOI https://doi.org/10.1016/j.bse.2024.104916.

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Official URL: https://doi.org/10.1016/j.bse.2024.104916

Abstract

The phytochemical studies on the bark of Cyathostemma wrayi King resulted in the identification of ten alkaloids consisting of four oxoaporphines; lysicamine (1), atherospermidine (2), thalicminine (3), liriodenine (4), five aporphines; xylopine (5), nornuciferine (6), annonaine (7), norstephalagine (8), asimilobine (9), and one propaporphine; stepharine (10). The structural characterisation of all the isolated alkaloids was confirmed through the analysis of spectroscopic data and comparison with literature data. This is the first report on the alkaloids of Cyathostemma wrayi and also the first report on the occurrence of aporphine (1-3) and proaporphine (5-10) alkaloids in the genus of Cyathostemma. In addition, the chemophenetic significance of the isolated alkaloids was summarized.

Item Type: Article
Funders: Universiti Malaya Research Grant (RK011-2020)
Uncontrolled Keywords: Annonaceae; Cyathostemma wrayi; Alkaloids; Aporphines
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Centre for Foundation Studies in Science > Chemistry Division
Faculty of Science > Department of Chemistry
Centre for Natural Products Research and Drug Discovery (CENAR)
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 21 Feb 2025 02:42
Last Modified: 21 Feb 2025 02:42
URI: http://eprints.um.edu.my/id/eprint/47332

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