Development and validation of the renal dosing questionnaire (RDQ-13) for pharmacists

Zafar, Roheena and Rehman, Inayat Ur and Shah, Yasar and Ming, Long Chiau and Hadi, Muhammad Abdul and Suleiman, Amal K. and Goh, Khang Wen (2024) Development and validation of the renal dosing questionnaire (RDQ-13) for pharmacists. Medicine, 103 (51). e41004. ISSN 0025-7974, DOI https://doi.org/10.1097/MD.0000000000041004.

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Official URL: https://doi.org/10.1097/MD.0000000000041004

Abstract

Pharmacists, as an integral part of the healthcare team, can play a crucial role in preventing drug-related problems in patients with chronic kidney disease that arise due to inappropriate doses. This study aimed to develop and validate a new tool, the renal dosing questionnaire (RDQ-13), for pharmacists working across hospital, community, and retail pharmacy settings. A cross-sectional study was conducted from January to March 2023 among pharmacists working in different settings. The RDQ-13 scale consists of 3-sections, encompassing demographic details, a knowledge section with 6 domains, each having 4 questions with the choice of ``yes/no,'' an attitude section featuring a Likert scale for 4 items, and a perception section featuring a Likert scale for 3 items. The assessment of construct and discriminative validity was performed along with testing for reliability. The average variance extracted value and the composite reliability value were used for convergent validity. A total of 65 pharmacists completed the RDQ-13, but at retest n = 2 participants were dropped (response rate at retest was 96.9%). Exploratory factor analysis revealed 3-factor loadings with 59.1% of the variance, whereas the Kaiser-Mayer-Olkin value was 0.60. The Cronbach alpha value of 0.700 indicates good internal consistency, whereas the intraclass correlation coefficient (ICC) for the test and retest showed that most domains/scores were statistically significant (P < .001), showing an excellent agreement between the test and retest. The RDQ-13 underwent extensive validation through a cross-sectional survey, demonstrating high content and face validity. The scale showed consistent responses over time (test-retest stability) and good internal consistency.

Item Type: Article
Funders: Sunway University Internal Grant Scheme (GRTIN-IGS(02)-DMS-12-2023)
Uncontrolled Keywords: construct validity; pharmacist; reliability; renal dose adjustment
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy > Department of Clinical Pharmacy and Pharmacy Practice
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 17 Mar 2025 03:39
Last Modified: 17 Mar 2025 03:39
URI: http://eprints.um.edu.my/id/eprint/47242

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