Zeeshan, Tayyaba and Qamar, Zeeshan and Abdul, Nishath Sayed and Soman, Cristalle and Bamousa, Badr and Marrapodi, Maria Maddalena and Cicciu, Marco and Minervini, Giuseppe (2024) The commercially available oral rinse vs. curcumin photosensitizers in an artificial mouth model mimicking their use after meals on early colonizers single species biofilm: An in vitro study. Technology and Health Care, 32 (4). pp. 2685-2696. ISSN 0928-7329, DOI https://doi.org/10.3233/THC-231814.
Full text not available from this repository.Abstract
BACKGROUND: Commercially available oral rinses contain active ingredients with concentration that is claimed by manufacturers to be effective as antiplaque agent. To date there has been no mention of the effect of oral rinse on the adherence of early plaque colonizers in plaque formation and the concentration to be used before/after meals. OBJECTIVE: The chief aim of the study was to evaluate microbial retention on the salivary pellicle on treatment with oral rinses (CHX & EO)/PS (mimicking after meals use of mouth wash/PS). METHODS: Noordini's Artifical Mouth model was used for developing the single species biofilm with early microbial colonizers of oral biofilm (A. viscosus, Strep. mitis and Strep. sanguinis respectively). The microbial retention on use of oral rinses comprising of CHX and EO as an active ingredients respectively was compared with Curcumin PS. For evaluating the microbial retention, the pellicle with microbial inoculation was developed on the glass beads in the mouth model. Subsequently the respective single specie biofilm was exposed to the mouth wash and PS after inoculation. It mimicked as use of mouth wash/PS after meals. The bacterial count in the dental biofilm was evaluated on serial dilution (CFU/ml). Sterile deionized water was used as a negative control. For qualitative analysis, Scanning electron microscope (SEM) was used to evaluate the microbial count. RESULTS: From the data it was observed that for the treatment of single species experimental biofilm with commercially available mouth rinses (CHX & EO) and PS (curcumin), there was significant retention for S.mitis, S.sanguinis and A.viscosus. There was no significant difference observed between PS and CHX treated single species biofilm. Whereas a significant difference was observed between EO treated biofilms and CHX/PS treated biofilms (p <= 0.05). CONCLUSION: It can be concluded from the results that curcumin PS and CHX should not be used after meals whereas EO containing mouth rinse can be used to maintain the oral mocroflora.
| Item Type: | Article |
|---|---|
| Funders: | University of Malaya, Kuala Lumpur, Malaysia and Riyadh Elm University, Riyadh, Saudi Arabia |
| Uncontrolled Keywords: | Bacterial retention; essential oils; chlorhexidine gluconate; curcumin photosensitizer |
| Subjects: | R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry > Department of Oral & Craniofacial Sciences |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 28 Nov 2024 05:21 |
| Last Modified: | 28 Nov 2024 05:21 |
| URI: | http://eprints.um.edu.my/id/eprint/47133 |
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