Chai, Chee-Shee and Ibrahim, Muhammad Amin and Azhar, Nur Amira and Roslan, Zulaika and Harun, Rozila and Krishnabahawan, Swarna Lata and Karthigayan, Aruna A. P. and Kadir, Roqiah Fatmawati Abdul and Johari, Busra and Ng, Diana-Leh-Ching and Sim, Benedict-Lim-Heng and Liam, Chong-Kin and Muttalif, Abdul Razak and Rasit, Ahmad Hata and Peariasamy, Kalaiarasu M. and Rani, Mohammed Fauzi Abdul (2024) Post-discharge spirometry evaluation in patients recovering from moderate-to-critical COVID-19: a cross-sectional study. Scientific Reports, 14 (1). p. 16413. ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-024-67536-2.
Full text not available from this repository.Abstract
Understanding the prevalence of abnormal lung function and its associated factors among patients recovering from COVID-19 is crucial for enhancing post-COVID care strategies. This study primarily aimed to determine the prevalence and types of spirometry abnormalities among post-COVID-19 patients in Malaysia, with a secondary objective of identifying its associated factors. Conducted at the COVID-19 Research Clinic, Faculty of Medicine, University Technology MARA, from March 2021 to December 2022, this study included patients at least three months post-discharge from hospitals following moderate-to-critical COVID-19. Of 408 patients studied, abnormal spirometry was found in 46.8%, with 28.4% exhibiting a restrictive pattern, 17.4% showing preserved ratio impaired spirometry (PRISm), and 1.0% displaying an obstructive pattern. Factors independently associated with abnormal spirometry included consolidation on chest X-ray (OR 8.1, 95% CI 1.75-37.42, p = 0.008), underlying cardiovascular disease (OR 3.5, 95% CI 1.19-10.47, p = 0.023), ground-glass opacity on chest X-ray (OR 2.6, 95% CI 1.52-4.30, p < 0.001), and oxygen desaturation during the 6-min walk test (OR 1.9, 95% CI 1.20-3.06, p = 0.007). This study highlights that patients recovering from moderate-to-critical COVID-19 often exhibit abnormal spirometry, notably a restrictive pattern and PRISm. Routine spirometry screening for high-risk patients is recommended.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaysia Sarawak |
| Uncontrolled Keywords: | COVID-19; Spirometry; Restrictive; Obstructive; PRISm; Radio-imaging |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 26 Mar 2025 07:39 |
| Last Modified: | 26 Mar 2025 07:39 |
| URI: | http://eprints.um.edu.my/id/eprint/46812 |
Actions (login required)
 |
View Item |
