Riyadi, Sandra Amalia and Naini, Al Arofatus and Mayanti, Tri and Farabi, Kindi and Harneti, Desi and Nurlelasari, - and Maharani, Rani and Lesmana, Ronny and Fajriah, Sofa and Jungsuttiwong, Siriporn and Awang, Khalijah and Azmi, Mohamad Nurul and Supratman, Unang (2024) Alliaceumolide A: A rare undescribed 17-membered macrolide from Indonesian Dysoxylum alliaceum. Phytochemistry Letters, 62. pp. 73-77. ISSN 1874-3900, DOI https://doi.org/10.1016/j.phytol.2024.07.004.
Full text not available from this repository.Abstract
Alliaceumolide A ( 1 ), a new macrolide together with known ivorenolide B ( 2 ) were isolated from Dysoxylum alliaceum (Blume) Blume ex A.Juss. These compounds were classified as 17-membered macrolide, which is a rare structure for plant-derived natural products. The structures were elucidated by extensive spectroscopic analyses, and the absolute configuration of 1 was determined by electronic circular dichroism (ECD) using TDDFT method. Furthermore, compounds 1 and 2 were tested for cytotoxic activity against two cancer MCF-7 and HeLa cell lines.
| Item Type: | Article |
|---|---|
| Funders: | Universitas Padjadjaran (1630/UN6.3.1/PT.00/2024) |
| Uncontrolled Keywords: | Dysoxylum alliaceum; Meliaceae; Alliaceumolide A; Macrolide; Cytotoxic |
| Subjects: | Q Science > QD Chemistry R Medicine > R Medicine (General) |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 26 Mar 2025 07:36 |
| Last Modified: | 26 Mar 2025 07:36 |
| URI: | http://eprints.um.edu.my/id/eprint/46811 |
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