Advancing thyroid care: An accurate trustworthy diagnostics system with interpretable AI and hybrid machine learning techniques

Sutradhar, Ananda and Akter, Sharmin and Shamrat, F. M. Javed Mehedi and Ghosh, Pronab and Zhou, Xujuan and Idris, Mohd Yamani Idna and Ahmed, Kawsar and Moni, Mohammad Ali (2024) Advancing thyroid care: An accurate trustworthy diagnostics system with interpretable AI and hybrid machine learning techniques. Heliyon, 10 (17). e36556. ISSN 2405-8440, DOI https://doi.org/10.1016/j.heliyon.2024.e36556.

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Abstract

The worldwide prevalence of thyroid disease is on the rise, representing a chronic condition that significantly impacts global mortality rates. Machine learning (ML) approaches have demonstrated potential superiority in mitigating the occurrence of this disease by facilitating early detection and treatment. However, there is a growing demand among stakeholders and patients for reliable and credible explanations of the generated predictions in sensitive medical domains. Hence, we propose an interpretable thyroid classification model to illustrate outcome explanations and investigate the contribution of predictive features by utilizing explainable AI. Two realtime thyroid datasets underwent various preprocessing approaches, addressing data imbalance issues using the Synthetic Minority Over-sampling Technique with Edited Nearest Neighbors (SMOTE-ENN). Subsequently, two hybrid classifiers, namely RDKVT and RDKST, were introduced to train the processed and selected features from Univariate and Information Gain feature selection techniques. Following the training phase, the Shapley Additive Explanation (SHAP) was applied to identify the influential characteristics and corresponding values contributing to the outcomes. The conducted experiments ultimately concluded that the presented RDKST classifier achieved the highest performance, demonstrating an accuracy of 98.98 % when trained on

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Thyroid disease; Machine learning; SMOTE-ENN; Ensemble methods; And explainable AI
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Divisions: Faculty of Computer Science & Information Technology > Department of Computer System & Technology
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 14 Apr 2025 07:05
Last Modified: 14 Apr 2025 07:05
URI: http://eprints.um.edu.my/id/eprint/46594

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