McEvoy, John William and Jennings, Catriona and Kotseva, Kornelia and De Bacquer, Dirk and De Backer, Guy and Erlund, Iris and Vihervaara, Terhi and Lip, Gregory Y. H. and Ray, Kausik K. and Ryden, Lars and Abreu, Ana and Almahmeed, Wael and Ambari, Ade Meidian and Ge, Junbo and Hasan-Ali, Hosam and Huo, Yong and Jankowski, Piotr and Jimenez, Rodney M. and Li, Yong and Mahmood Zuhdi, Ahmad Syadi and Makubi, Abel and Mbakwem, Amam Chinyere and Mbau, Lilian and Estrada, Jose Luis Navarro and Ogah, Okechukwu Samuel and Ogola, Elijah Nyainda and Quintero-Baiz, Adalberto and Sani, Mahmoud Umar and Liprandi, Maria Ines Sosa and Tan, Jack Wei Chieh and Triana, Miguel Alberto Urina and Yeo, Tee Joo and Ganly, Sandra and Adamska, Agnieszka and Wood, David and Investigators, INTERASPIRE (2024) Variation in secondary prevention of coronary heart disease: the INTERASPIRE study. European Heart Journal, 45 (39). pp. 4184-4196. ISSN 0195-668X, DOI https://doi.org/10.1093/eurheartj/ehae558.
Full text not available from this repository.Abstract
Background and Aims INTERASPIRE is an international study of coronary heart disease (CHD) patients, designed to measure if guideline standards for secondary prevention and cardiac rehabilitation are being achieved in a timely manner. Methods Between 2020 and 2023, adults hospitalized in the preceding 6-24 months with incident or recurrent CHD were sampled in 14 countries from all 6 World Health Organization regions and invited for a standardized interview and examination. Direct age and sex standardization was used for country-level prevalence estimation. Results Overall, 4548 (21.1% female) CHD patients were interviewed a median of 1.05 (interquartile range .76-1.45) years after index hospitalization. Among all participants, 24.6% were obese (40.7% centrally). Only 38.6% achieved a blood pressure (BP) < 130/80 mmHg and 16.6% a LDL cholesterol (LDL-C) of <1.4 mmol/L. Of those smoking at hospitalization, 48% persisted at interview. Of those with known diabetes, 55.2% achieved glycated haemoglobin (HbA1c) of <7.0%. A further 9.8% had undetected diabetes and 26.9% impaired glucose tolerance. Females were less likely to achieve the targets: BP (females 36.8%, males 38.9%), LDL-C (females 12.0%, males 17.9%), and HbA1c in diabetes (females 47.7%, males 57.5%). Overall, just 9.0% (inter-country range 3.8%-20.0%) reported attending cardiac rehabilitation and 1.0% (inter-country range .0%-2.4%) achieved the study definition of optimal guideline adherence. Conclusions INTERASPIRE demonstrates inadequate and heterogeneous international implementation of guideline standards for secondary prevention in the first year after CHD hospitalization, with geographic and sex disparity. Investment aimed at reducing between-country and between-individual variability in secondary prevention will promote equity in global efforts to reduce the burden of CHD.
| Item Type: | Article |
|---|---|
| Funders: | Abbott Laboratories, Asian Pacific Society of Cardiology, European Atherosclerosis Society, Pan-African Society of Cardiology, World Heart Federation |
| Uncontrolled Keywords: | Coronary heart disease; Secondary prevention; Guideline implementation; Global health equity; Observational research |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Universiti Malaya Medical Centre (UMMC) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 14 Apr 2025 07:22 |
| Last Modified: | 14 Apr 2025 07:22 |
| URI: | http://eprints.um.edu.my/id/eprint/46587 |
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