Morphologic and molecular identification of human ocular infection caused by Pelecitus Nematodes, Thailand

Rujkorakarn, Ploysai and Suvannachart, Pukkapol and Patamatamkul, Samadhi and Thanchomnang, Tongjit and Pramual, Pairot and Saijuntha, Weerachai and Maleewong, Wanchai and Uni, Shigehiko (2024) Morphologic and molecular identification of human ocular infection caused by Pelecitus Nematodes, Thailand. Emerging Infectious Diseases, 30 (9). ISSN 1080-6040, DOI https://doi.org/10.3201/eid3009.231692.

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Abstract

Nematodes of the Onchocercidae family, such as Peleci-tus spp., are filarial parasites of medical and veterinary importance. Although infections are widely distributed among avian species, only 2 cases of human Peleci-tus ocular infection, both in South America, have been reported. We describe a 61-year-old man in northeast Thailand diagnosed with an ocular infection. Morpho-logic characteristics suggested the causative agent was a female Pelecitus nematode: coiled body, rounded an-terior and posterior extremities, a distinct preesophageal cuticular ring, lateral alae, a postdeirid, and a protuber-ant vulva. Sequences of the 12S rDNA gene indicated 95%-96% identity and cox1 gene 92%-96% identity with published P. copsychi sequences. P-distance for cox1 sequences between the causative agent and P. copsychiwas 6.71%. Phylogenetic trees of 12S rDNA and cox1 genes indicated the species differed from but is closely associated with P. copsychi. Healthcare providers should be aware of the threat of ocular infection from Pelecitus spp. nematodes.

Item Type: Article
Funders: None
Uncontrolled Keywords: Nematodes; Onchocercidae family; Filarial parasites; Veterinary
Subjects: Q Science > QR Microbiology > QR180 Immunology
Q Science > QR Microbiology > QR355 Virology
Divisions: Universiti Malaya
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 06 Oct 2025 01:52
Last Modified: 06 Oct 2025 01:52
URI: http://eprints.um.edu.my/id/eprint/46570

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