Determining direct, indirect healthcare and social costs for diabetic retinopathy management: A systematic review

Benhamza, Mawdda and Dahlui, Maznah and Said, Mas Ayu (2024) Determining direct, indirect healthcare and social costs for diabetic retinopathy management: A systematic review. BMC Ophthalmology, 24 (1). ISSN 1471-2415, DOI https://doi.org/10.1186/s12886-024-03665-6.

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Abstract

IntroductionDiabetic retinopathy (DR) is a rapidly growing global public health threat; it affects 1 in 3 people with diabetes and is still the leading cause of blindness among the working-age population. The management of diabetic retinopathy is becoming more advanced and effective but is highly expensive compared to other ocular diseases.AimTo report direct medical, indirect medical, and nonmedical costs of diabetic retinopathy in developed and developing countries through a systematic review.MethodsRelated articles published in the PubMed, Google Scholar, and EMBASE electronic databases from 1985 to 2022 were identified using the keywords direct medical and indirect medical and social costs of diabetic retinopathy. However, previous systematic reviews, abstracts, and case reports were excluded.ResultsThirteen articles were eligible for assessing the economic burden of diabetes management and its complications. Our analysis revealed that increasing prevalence and severity of diabetic retinopathy (DR) are associated with higher direct and indirect healthcare expenditures. The impact of DR on working-age adults, leading to irreversible blindness in advanced stages, underscores the urgent need for cost-effective prevention and management strategies.DiscussionThis study systematically reviewed the direct medical, indirect medical, and nonmedical costs of DR in developed and developing countries. Our findings highlight the significant economic burden of DR, emphasizing the importance of implementing effective prevention and management measures to alleviate costs and enhance patient outcomes.ConclusionThe substantial financial burden of DR necessitates a re-evaluation of current screening and management programs. Revision of these programs is crucial to improve quality of care, reduce costs, and ultimately achieve Sustainable Development Goal 3, which aims to ensure good health and well-being for all.

Item Type: Article
Funders: Universiti Malaya
Uncontrolled Keywords: Diabetes; Diabetic retinopathy; Direct medical cost; Indirect medical cost; And indirect nonmedical cost
Subjects: R Medicine
Divisions: Faculty of Medicine > Social & Preventive Medicine
Universiti Malaya Medical Centre (UMMC)
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 26 Oct 2025 04:04
Last Modified: 26 Oct 2025 04:04
URI: http://eprints.um.edu.my/id/eprint/46434

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