Yi, Qing and Liu, Zuhong and Zhong, Fei and Selvanayagam, Victor Selvarajah and Cheong, Jadeera Phaik Geok (2024) Cognitive and physical impact of combined exercise and cognitive intervention in older adults with mild cognitive impairment: A systematic review and meta-analysis. PLoS ONE, 19 (10). ISSN 1932-6203, DOI https://doi.org/10.1371/journal.pone.0308466.
Full text not available from this repository.Abstract
Emerging studies have examined the effectiveness of combined exercise and cognitive intervention (combined intervention) on the cognitive function of older adults with MCI, but the conclusions remain disputed. Our study aimed to comprehensively examine the efficacy of the combined intervention on cognitive and physical function in older adults with MCI. PubMed, Cochrane Library, EMBASE, and PsycINFO were retrieved to identify the relevant articles. Twelve eligible studies were included, and the results showed that combined intervention significantly improved global cognition SMD = 0.26, 95% CI 0.14-0.39], p<0.0001), executive function (SMD = 0.40, 95% CI 0.25-0.56], p < 0.00001), memory (SMD = 0.30, 95% CI 0.22-0.39], p <0.00001), and gait performance (SMD = 0.32, 95% CI 0.03-0.62], P = 0.03) compared to the control group. Combined intervention significantly improved executive function compared to single exercise intervention while not showing a statistically significant difference compared to single cognitive intervention. Moreover, no significant difference was observed between simultaneously and sequentially combined intervention. The finding indicated that combined intervention is efficacious in improving global cognition and selectively enhancing cognitive domains and physical function in older adults with MCI. More research with robust designs should be conducted, particularly involving comparisons with single interventions and different types of combined interventions.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Dementia; People; Power; Cognitive intervention; Older adults |
| Subjects: | R Medicine > RC Internal medicine > RC1200 Sports Medicine |
| Divisions: | Faculty of Sports and Exercise Science (formerly known as Centre for Sports & Exercise Sciences) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 29 Oct 2025 08:19 |
| Last Modified: | 29 Oct 2025 08:19 |
| URI: | http://eprints.um.edu.my/id/eprint/46394 |
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