Yap, Kah Hui and Baharudin, Nurul Husna and Gafor, Abdul Halim Abdul and Remli, Rabani and Lim, Shen-Yang and Zaidi, Wan Asyraf Wan and Azmin, Shahrul and Mukari, Shahizon Azura Mohamed and Khalid, Raihanah Abdul and Ibrahim, Norlinah Mohamed (2022) Movement disorders resulting from bilateral basal ganglia lesions in end-stage kidney disease: A systematic review. Journal of Movement Disorders, 15 (3). 258+. ISSN 2005-940X, DOI https://doi.org/10.14802/jmd.21185.
Full text not available from this repository.Abstract
Objective The basal ganglia (BG) are susceptible to fluctuations in blood urea levels, sometimes resulting in movement disor-ders. We described patients with end-stage kidney disease (ESKD) presenting with movement disorders associated with bilateral BG lesions on imaging. Methods We report four patients and systematically reviewed all published cases of ESKD presenting with movement disor-ders and bilateral BG lesions (EBSCOhost and Ovid). Results Of the 72 patients identified, 55 (76.4%) were on regular dialysis. Parkinsonism was the most common movement disorder (n = 39; 54.2%), followed by chorea (n = 24; 33.3%). Diabetes mellitus (n = 51; 70.8%) and hypertension (n = 16; 22.2%) were the most common risk factors. Forty-three (59.7%) were of Asian ethnicity. Complete clinical resolution was reported in 17 (30.9%) patients, while 38 (69.1%) had incomplete clinical resolution with relapse. Complete radiological resolution occurred in 14 (34.1%) patients. Conclusion Movement disorders associated with BG lesions should be recognized as a rare and potentially reversible meta-bolic movement disorder in patients with ESKD
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Basal ganglia; Chorea; End-stage kidney disease; Magnetic resonance imaging; Parkinsonism |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms Koh Ai Peng |
| Date Deposited: | 23 Jul 2024 04:58 |
| Last Modified: | 23 Jul 2024 04:58 |
| URI: | http://eprints.um.edu.my/id/eprint/46260 |
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