Asghar, Mehmood and Yahya, Rosiyah and Yap, Adrian U. Jin and Azzahari, Ahmad Danial and Omar, Ros Anita (2022) Incorporation of green capping agents to reduce silver-mediated dentine staining. CARIES RESEARCH, 56 (3). pp. 149-160. ISSN 1421-976X, DOI https://doi.org/10.1159/000525505.
Full text not available from this repository.Abstract
Silver diammine fluoride (SDF) is known as a noninvasive, cost-effective, safe, and simple method of dental caries treatment. However, staining and discoloration seem inseparable with SDF and continue as a cosmetic concern. Research is ongoing to overcome these issues, for example, by using glutathione (G) or potassium iodide among others. Therefore, the study aimed to investigate the effects of incorporating different concentrations of capping agents on SDF chemistry and SDF-mediated tooth staining at different time points. Tannic acid (TA), gallic acid (GA), carboxymethyl chitosan (CM), and G at different concentrations (5, 10, and 15% w/v) were incorporated in 30% SDF. FTIR and UV-Vis spectroscopies of the prepared solutions was performed to evaluate chemical changes. Time-dependent color changes (Delta E) in bovine dentine specimens (6 x 6 x 1 +/- 0.25 mm(3)) were measured spectrophotometrically at application/washup, 1 and 3 h, after 1, 2, 4, 7, and 14 days. Results showed suppression of FTIR peaks at 3,358 cm(-1) and 1,215 cm(-1) in capping agent-modified SDF indicative of a successful capping effect of the silver ions, which was corroborated by UV-Vis blueshift of similar to increment 32 nm. The capping effect on SDF increased proportionally with the concentrations of TA, GA, CM, and G used. A more pronounced tooth staining reduction however was shown more in TA- and G- rather than in GA- and CM-modified SDF. At day 14, SDF showed the highest mean Delta E(50.14 +/- 2.14), while 15% TA showed the lowest Delta E(30.14 +/- 0.81). In conclusion, capping agent incorporation significantly reduced SDF-mediated tooth staining. This reduction in staining is more dependent on the respective capping agent functional groups than concentrations per se. The potential of capping agents to minimize tooth staining of SDF was TA>G>CM>GA.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya [GPF010E-2019] |
| Uncontrolled Keywords: | Capping agents; Tooth staining; Minimally invasive dentistry; Color change; Silver diammine fluoride |
| Subjects: | R Medicine > RK Dentistry |
| Divisions: | Centre for Foundation Studies in Science Faculty of Dentistry > Department of Restorative Dentistry Faculty of Science > Department of Chemistry |
| Depositing User: | Ms Koh Ai Peng |
| Date Deposited: | 22 Oct 2024 07:08 |
| Last Modified: | 22 Oct 2024 07:08 |
| URI: | http://eprints.um.edu.my/id/eprint/46192 |
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