Primus, Phoebe Sussana and Wu, Carol Hsin-Yi and Kao, Chai-Lin and Choo, Yeun-Mun (2024) Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton. Natural Product Research, 38 (8). pp. 1406-1413. ISSN 1478-6419, DOI https://doi.org/10.1080/14786419.2022.2147932.
Full text not available from this repository.Abstract
Two new bisanthraquinones, glabraquinone A and B (1-2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5), nordamnacanthal (6), damnacanthal (7) and 2-carboxaldehyde-3-hydroxyanthraquinone (8)) and an aromatic compound, that is, catechol diethyl ether (9) were isolated and characterized in this study. Compounds 1, 4 and 9 showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Prismatomeris glabra (Korth; ) Valeton; Rubiaceae; Glabraquinones; Bisanthraquinones; Anthraquinones; Anti-neuroblastoma |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 13 Aug 2024 06:53 |
| Last Modified: | 13 Aug 2024 06:53 |
| URI: | http://eprints.um.edu.my/id/eprint/46089 |
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