Shear wave elastography in chronic kidney disease: The physics and clinical application

Ng, Kwan Hoong and Wong, Jeannie Hsiu Ding and Leong, Sook Sam (2024) Shear wave elastography in chronic kidney disease: The physics and clinical application. Physical and Engineering Sciences in Medicine, 47 (1). pp. 17-29. ISSN 2662-4729, DOI https://doi.org/10.1007/s13246-023-01358-w.

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Abstract

Chronic kidney disease is a leading public health problem worldwide. The global prevalence of chronic kidney disease is nearly five hundred million people, with almost one million deaths worldwide. Estimated glomerular filtration rate, imaging such as conventional ultrasound, and histopathological findings are necessary as each technique provides specific information which, when taken together, may help to detect and arrest the development of chronic kidney disease, besides managing its adverse outcomes. However, estimated glomerular filtration rate measurements are hampered by substantial error margins while conventional ultrasound involves subjective assessment. Although histopathological assessment is the best tool for evaluating the severity of the renal pathology, it may lead to renal insufficiency and haemorrhage if complications occurred. Ultrasound shear wave elastography, an emerging imaging that quantifies tissue stiffness non-invasively has gained interest recently. This method applies acoustic force pulses to generate shear wave within the tissue that propagate perpendicular to the main ultrasound beam. By measuring the speed of shear wave propagation, the tissue stiffness is estimated. This paper reviews the literature and presents our combined experience and knowledge in renal shear wave elastography research. It discusses and highlights the confounding factors on shear wave elastography, current and future possibilities in ultrasound renal imaging and is not limited to new sophisticated techniques.

Item Type: Article
Funders: Universiti Teknologi MARA
Uncontrolled Keywords: Shear wave; Elastography; Physics; Ultrasound; Kidney; Imaging
Subjects: R Medicine
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 12 Aug 2024 03:10
Last Modified: 12 Aug 2024 03:10
URI: http://eprints.um.edu.my/id/eprint/45958

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