From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses

Barathan, Muttiah (2024) From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses. Pathogens and Disease, 82. ftae006. ISSN 2049-632X, DOI https://doi.org/10.1093/femspd/ftae006.

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Official URL: https://doi.org/10.1093/femspd/ftae006

Abstract

Acute Undifferentiated Febrile Illness (AUFI) presents a clinical challenge, often characterized by sudden fever, non-specific symptoms, and potential life-threatening implications. This review highlights the global prevalence, types, challenges, and implications of AUFI, especially in tropical and subtropical regions where infectious diseases thrive. It delves into the difficulties in diagnosis, prevalence rates, regional variations, and potential causes, ranging from bacterial and viral infections to zoonotic diseases. Furthermore, it explores treatment strategies, preventive measures, and the critical role of the One Health approach in addressing AUFI. The paper also addresses the emerging zoonotic risks and ongoing outbreaks, including COVID-19, Rickettsia spp., and other novel pathogens, emphasizing their impact on AUFI diagnosis and management. Challenges in resource-limited settings are analyzed, highlighting the need for bolstered healthcare infrastructure, enhanced diagnostics, and collaborative One Health strategies. Amidst the complexity of emerging zoonotic threats, this review underscores the urgency for a multifaceted approach to mitigate the growing burden of AUFI, ensuring early diagnosis, appropriate treatment, and effective prevention strategies. Unveiling Acute Undifferentiated Febrile Illness: Global Prevalence, Challenges, and One Health Strategies for Emerging Zoonotic Threats in Resource-Limited Settings.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: acute; febrile; respiratory; unidentified; and delayed
Subjects: Q Science > QR Microbiology
Q Science > QR Microbiology > QR180 Immunology
Q Science > QR Microbiology > QR355 Virology
R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Medical Microbiology Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 07 Nov 2024 06:25
Last Modified: 07 Nov 2024 06:25
URI: http://eprints.um.edu.my/id/eprint/45650

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