An observational study of olfactory functions in total laryngectomees

Bee, Cho Yin and Ahmad, Tengku Ezulia binti Tengku Nun and Lim, Chee Chean and Abu Bakar, Mohd Zulkiflee (2024) An observational study of olfactory functions in total laryngectomees. European Archives of Oto-Rhino-Laryngology, 281 (5). pp. 2515-2521. ISSN 0937-4477, DOI https://doi.org/10.1007/s00405-024-08514-2.

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Official URL: https://doi.org/10.1007/s00405-024-08514-2

Abstract

ObjectiveTo evaluate the olfactory acuity and quality of life in patients who have undergone total laryngectomy. The study also aims to identify any specific patient-related risk factors linked to worse olfactory outcomes.MethodsThis is a prospective cross-sectional study conducted at the University Malaya Medical Centre. A total of 30 patients who have undergone total laryngectomy were assessed objectively using the Sniffin' Sticks test and compared against normal age-matched Malaysians. Subsequently, they also filled out the modified Questionnaire on Olfactory Disorders. Correlations of patient demographics, disease and treatment variables against olfactory outcomes were conducted.ResultsAll subjects suffered olfactory impairment, with 66.7% of them being anosmic after total laryngectomy. The Sniffin' Sticks test demonstrated a statistically significant difference between laryngectomees and the normal age-matched Malaysian population in all three subtests for odor threshold, discrimination and identification. 37% of patients developed olfactory adaptive methods, which resulted in higher olfactory scores and a better quality of life. There were no patient demographics, disease or treatment variables associated with a poorer olfactory outcome identified.ConclusionOlfactory impairment should not be overlooked among patients after total laryngectomy. Although as many as a third of patients developed some sort of olfactory adaptive behavior, early rehabilitation should be integrated into the multidisciplinary rehabilitation program after total laryngectomy.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Olfactory; Sniffin' sticks; Total laryngectomees; Quality of life; Olfactory adaptive methods; Rehabilitation
Subjects: R Medicine > R Medicine (General)
R Medicine > RF Otorhinolaryngology
Divisions: Faculty of Medicine > Otorhinolaryngology Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Oct 2024 06:49
Last Modified: 22 Oct 2024 06:49
URI: http://eprints.um.edu.my/id/eprint/45475

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