Kai, Lim Chin and Khaliddin, Nurliza and Hassan, Muhammad Kamil and Hariri, Firdaus (2024) Skeletal expansion via craniofacial distraction osteogenesis technique in syndromic craniosynostosis: impact on ophthalmic parameters. International Ophthalmology, 44 (1). p. 147. ISSN 0165-5701, DOI https://doi.org/10.1007/s10792-024-03084-y.
Full text not available from this repository.Abstract
BackgroundThis study aims to compare the changes in ophthalmic parameters among syndromic craniosynostosis patients who underwent craniofacial skeletal expansion procedures via distraction osteogenesis (DO).MethodA retrospective study was conducted involving syndromic craniosynostosis patients who underwent surgical expansion via the DO technique from the year 2012 to March 2022. Changes in six parameters which consist of visual acuity, refractive error, optic disc health, intraocular pressure, degree of proptosis and orbital volume were measured objectively pre and post-surgery. For categorical parameters, the Chi-square cross-tab test was done. Paired sample T-test was used for normally distributed variables. Wilcoxon signed-rank test was used for non-normally distributed data.ResultsVisual impairment was present in 21.4% of eyes before surgery and increased to 28.5% post-surgery. Three patients had changes of refractive error post-surgery with one developed hypermetropia, another developed anisometropia and the last had improvement to no refractive error. Two patients had optic disc swelling which was resolved post-surgery. Intraocular pressure changes were inconsistent post-surgery. All patients achieved a significant reduction in the degree of proptosis post-surgery. Orbital volume calculation using computed tomography (CT) scans shows a significant increase in volume post-surgery for all patients.ConclusionOur study shows a significant increase in orbital volume post-surgery with a reduction in the degree of proptosis. Optic disc and nerve health improved after the surgery. Changes in terms of visual acuity, refractive error and IOP were inconsistent after the surgical intervention.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Craniosynostoses; Exophthalmos; Distraction osteogenesis; Orbit; Tomography; X ray computed |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RE Ophthalmology R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry > Dept of Oral & Maxillofacial Surgery Faculty of Medicine > Department of Ophthalmology |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 21 Oct 2024 07:50 |
| Last Modified: | 21 Oct 2024 07:50 |
| URI: | http://eprints.um.edu.my/id/eprint/45427 |
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