Seow, Shi Rui and Mat, Sumaiyah and Azam, Amalina Ahmad and Rajab, Nor Fadilah and Ismail, Intan Safinar and Singh, Devinder Kaur Ajit and Shahar, Suzana and Tan, Maw Pin and Berenbaum, Francis (2024) Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers. Expert Reviews in Molecular Medicine, 26. e8. ISSN 1462-3994, DOI https://doi.org/10.1017/erm.2024.7.
Full text not available from this repository.Abstract
Osteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs 1, 2). Early management is important in order to avoid disability uphold quality of life (Ref. 3). However, a lack of awareness of subclinical and early symptomatic stages of OA often hampers early management (Ref. 4). Moreover, late diagnosis of OA among those with severe disease, at a stage when OA management becomes more complicated is common (Refs 5, 6, 7, 8). Established risk factors for the development and progression of OA include increasing age, female, history of trauma and obesity (Ref. 9). Recent studies have also drawn a link between OA and metabolic syndrome, which is characterized by insulin resistance, dyslipidaemia and hypertension (Refs 10, 11).
| Item Type: | Article |
|---|---|
| Funders: | Fundamental Research Grant Scheme, Ministry of Higher Education, Malaysia (FRGS/1/2021/SKK0/UKM/02/15) |
| Uncontrolled Keywords: | biomarkers; diabetes mellitus; inflammation; metabolism; osteoarthritis |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 08 Oct 2024 07:04 |
| Last Modified: | 08 Oct 2024 07:04 |
| URI: | http://eprints.um.edu.my/id/eprint/45318 |
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