Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.

Ho, Siaw Eng; Subramaniam, Geetha; Palasubramaniam, Selvi; Navaratnam, Parasakthi (2002) Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. Antimicrobial agents and chemotherapy, 46 (10). pp. 3286-7. ISSN 0066-4804

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Abstract

We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant.

Item Type: Article
Creators:
  1. Ho, Siaw Eng
  2. Subramaniam, Geetha
  3. Palasubramaniam, Selvi
  4. Navaratnam, Parasakthi
Journal or Publication Title: Antimicrobial agents and chemotherapy
Uncontrolled Keywords: Anti-Bacterial Agents/pharmacology; Carbapenems/pharmacology;
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 10 Mar 2011 09:27
Last Modified: 10 Mar 2011 09:27
URI: http://eprints.um.edu.my/id/eprint/452

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