Mousavi, Seyyed Mojtaba and Kalashgrani, Masoomeh Yari and Binazadeh, Mojtaba and Mazaheri, Yousef and Omidifar, Navid and Rahmanian, Vahid and Riazi, Mohsen and Lai, Chin Wei and Althomali, Raed H. and Rahman, Mohammed M. and Gholami, Ahmad and Chiang, Wei-Hung (2024) Recent advancements in smart MXene quantum dot-based nanosystems for immunomodulatory and effective cancer treatment. Materials Today Chemistry, 38. p. 102097. ISSN 2468-5194, DOI https://doi.org/10.1016/j.mtchem.2024.102097.
Full text not available from this repository.Abstract
MXene quantum dots (MQDs) are a novel generation of smart nanosystems for various biomedical and pharmaceutical applications, such as biological imaging/sensing, tissue engineering, cancer diagnostics/therapy, analytical biochemistry, and drug/gene delivery, owing to their specific instinct characteristics and biocompatibility. However, there are several challenges related to their histopathology, long-term toxicity, biodegradability, photoluminescence (especially in clinical studies), and biodistribution properties, which must be carefully assessed. In addition to developing highly scalable and optimized synthesis methods for MQD-based nanosystems, more advanced smart MXene-based platforms and their hybrid nanocomposites must be developed to address the uprising requirements. A smart nanosystem based on MQDs with improved properties requires advanced functionalization strategies, improved synthesis methods, and cytotoxicity/biosafety evaluations. The current review article highlighted recent developments in the immunomodulatory cancer applications of MQDs, focusing on current trends and future perspectives.
| Item Type: | Article |
|---|---|
| Funders: | National Science and Technology Council, Taiwan (NSTC 111-2223-E-011-002-MY3) ; (NSTC 111-2628-E-011-002-MY2) ; (NSTC 113-2927-I-011-504), Ministry of Education, Taiwan ("Sustainable Electrochemical Energy Development Center" (SEED) project), National Taiwan University of Science and Technology, Prince Sattam bin Abdulaziz University (PSAU/2023/R/1444) |
| Uncontrolled Keywords: | MXene quantum dots; Smart quantum dots; Immune system; Cancer treatment; Nanosystems |
| Subjects: | Q Science > QD Chemistry T Technology > TP Chemical technology |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 25 Sep 2024 08:33 |
| Last Modified: | 25 Sep 2024 08:33 |
| URI: | http://eprints.um.edu.my/id/eprint/45194 |
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