Khairunnisa, Z. and Tuygunov, N. and Cahyanto, A. and Aznita, W.H. and Purwasena, I.A. and Noor, N.S.M. and Azami, N.H. and Zakaria, Myrna Nurlatifah (2024) Potential of microbial-derived biosurfactants for oral applications-a systematic review. BMC Oral Health, 24 (1). p. 707. ISSN 1472-6831, DOI https://doi.org/10.1186/s12903-024-04479-0.
Full text not available from this repository.Abstract
Background Biosurfactants are amphiphilic compounds produced by various microorganisms. Current research evaluates diverse types of biosurfactants against a range of oral pathogens.Objectives This systematic review aims to explore the potential of microbial-derived biosurfactants for oral applications.Methodology A systematic literature search was performed utilizing PubMed-MEDLINE, Scopus, and Web of Science databases with designated keywords. The results were registered in the PROSPERO database and conducted following the PRISMA checklist. Criteria for eligibility, guided by the PICOS framework, were established for both inclusion and exclusion criteria. The QUIN tool was used to assess the bias risk for in vitro dentistry studies.Results Among the initial 357 findings, ten studies were selected for further analysis. The outcomes of this systematic review reveal that both crude and purified forms of biosurfactants exhibit antimicrobial and antibiofilm properties against various oral pathogens. Noteworthy applications of biosurfactants in oral products include mouthwash, toothpaste, and implant coating.Conclusion Biosurfactants have garnered considerable interest and demonstrated their potential for application in oral health. This is attributed to their surface-active properties, antiadhesive activity, biodegradability, and antimicrobial effectiveness against a variety of oral microorganisms, including bacteria and fungi.
| Item Type: | Article |
|---|---|
| Funders: | Fundamental Research Grant Scheme (FRGS/1/2022/SKK11/UM/03/3), Ministry of Higher Education for the Fundamental Research Grant Scheme, Universiti Malaya |
| Uncontrolled Keywords: | Antimicrobial; Biofilm; Minimum inhibitory concentration; Oral health; Oral pathology; Surface-active agent |
| Subjects: | R Medicine > RK Dentistry R Medicine > RK Dentistry > Oral surgery |
| Divisions: | Faculty of Dentistry > Department of Oral & Craniofacial Sciences |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 19 Sep 2024 07:32 |
| Last Modified: | 19 Sep 2024 07:32 |
| URI: | http://eprints.um.edu.my/id/eprint/45143 |
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