Ahmadipour, Mohsen and Bhattacharya, Anish and Sarafbidabad, Mohsen and Syuhada Sazali, Ezza and Krishna Ghoshal, Sib and Satgunam, Meenaloshini and Singh, Ramesh and Rezaei Ardani, Mohammad and Missaoui, Nadhem and Kahri, Hamza and Pal, Ujjwal and Ling Pang, Ai (2024) CA19-9 and CEA biosensors in pancreatic cancer. Clinica Chimica Acta, 554. ISSN 0009-8981, DOI https://doi.org/10.1016/j.cca.2024.117788.
Full text not available from this repository.Abstract
Cancer is a complex pathophysiological condition causing millions of deaths each year. Early diagnosis is essential especially for pancreatic cancer. Existing diagnostic tools rely on circulating biomarkers such as Carbohydrate Antigen 19–9 (CA19-9) and Carcinoembryonic Antigen (CEA). Unfortunately, these markers are nonspecific and may be increased in a variety of disorders. Accordingly, diagnosis of pancreatic cancer generally involves more invasive approaches such as biopsy as well as imaging studies. Recent advances in biosensor technology have allowed the development of precise diagnostic tools having enhanced analytical sensitivity and specificity. Herein we examine these advances in the detection of cancer in general and in pancreatic cancer specifically. Furthermore, we highlight novel technologies in the measurement of CA19-9 and CEA and explore their future application in the early detection of pancreatic cancer. © 2024 Elsevier B.V.
| Item Type: | Article |
|---|---|
| Funders: | Tenaga Nasional Berhad, Universiti Tunku Abdul Rahman [Grant no. IPSR/RMC/UTARRF/2023-C1/P02], Universiti Tenaga Nasional [Grant no. J510050002-IC-6 BOLDREFRESH2025-center] |
| Uncontrolled Keywords: | Biosensors; Cancer biomarker; Cancer detection; Clinical Diagnostics; Nanomaterials; Point-of-care |
| Subjects: | T Technology > TJ Mechanical engineering and machinery |
| Divisions: | Faculty of Engineering > Department of Mechanical Engineering |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 14 Jun 2024 06:59 |
| Last Modified: | 14 Jun 2024 06:59 |
| URI: | http://eprints.um.edu.my/id/eprint/44875 |
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