Chong, Chun Yip and Bustam, Aida and Noor Azhar, Muhaimin and Abdul Latif, Abd Kursi and Ismail, Ramzuzaman and Poh, Khadijah (2024) Evaluation of HACOR scale as a predictor of non-invasive ventilation failure in acute cardiogenic pulmonary oedema patients: A prospective observational study. American Journal of Emergency Medicine, 79. 19 – 24. ISSN 0735-6757, DOI https://doi.org/10.1016/j.ajem.2024.01.044.
Full text not available from this repository.Abstract
Background and importance: Acute cardiogenic pulmonary oedema (ACPO) is a common indication for non-invasive ventilation (NIV) in the emergency department (ED). HACOR score of >5 is used to predict NIV failure. The predictive ability of HACOR may be affected by altered physiological parameters in ACPO patients due to medications or comorbidities. Objectives: To validate the HACOR scale in predicting NIV failure among acute cardiogenic pulmonary oedema (ACPO) patients. Design, settings and participants: This is a prospective, observational study of consecutive ACPO patients requiring NIV admitted to the ED. Outcome measure and analysis: Primary outcome was the ability of the HACOR score to predict NIV failure. Clinical, physiological, and HACOR score at baseline and at 1 h, 12 h and 24 h were analysed. Other potential predictors were assessed as secondary outcomes. Main results: A total of 221 patients were included in the analysis. Fifty-four (24.4) had NIV failure. Optimal HACOR score was >5 at 1 h after NIV initiation in predicting NIV failure (AUC 0.73, sensitivity 53.7, specificity 83.2). As part of the HACOR score, respiratory rate and heart rate were not found to be significant predictors. Other significant predictors of NIV failure in ACPO patients were acute coronary syndrome, acute kidney injury, presence of congestive heart failure as a comorbid, and the ROX index. Conclusions: The HACOR scale measured at 1 h after NIV initiation predicts NIV failure among ACPO patients with acceptable accuracy. The cut-off level > 5 could be a useful clinical decision support tool in ACPO patient. However, clinicians should consider other factors such as the acute coronary and acute kidney diagnosis at presentation, presence of underlying congestive heart failure and the ROX index when clinically deciding on timely invasive mechanical ventilation. © 2024 Elsevier Inc.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Acute cardiogenic pulmonary oedema; Emergency; HACOR; NIV failure; Non-invasive ventilation; ROX |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 12 Jul 2024 07:21 |
| Last Modified: | 12 Jul 2024 07:21 |
| URI: | http://eprints.um.edu.my/id/eprint/44787 |
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