Venkatraman, Gopinath and Giribabu, Nelli and Mohan, Priyadarshini Sakthi and Muttiah, Barathan and Govindarajan, Venkat Kumar and Alagiri, Mani and Abdul Rahman, Puteri Shafinaz and Karsani, Saiful Anuar (2024) Environmental impact and human health effects of polycyclic aromatic hydrocarbons and remedial strategies: A detailed review. Chemosphere, 351. ISSN 0045-6535, DOI https://doi.org/10.1016/j.chemosphere.2024.141227.
Full text not available from this repository.Abstract
Polycyclic Aromatic Hydrocarbons (PAHs) profoundly impact public and environmental health. Gaining a comprehensive understanding of their intricate functions, exposure pathways, and potential health implications is imperative to implement remedial strategies and legislation effectively. This review seeks to explore PAH mobility, direct exposure pathways, and cutting-edge bioremediation technologies essential for combating the pervasive contamination of environments by PAHs, thereby expanding our foundational knowledge. PAHs, characterised by their toxicity and possession of two or more aromatic rings, exhibit diverse configurations. Their lipophilicity and remarkable persistence contribute to their widespread prevalence as hazardous environmental contaminants and byproducts. Primary sources of PAHs include contaminated food, water, and soil, which enter the human body through inhalation, ingestion, and dermal exposure. While short-term consequences encompass eye irritation, nausea, and vomiting, long-term exposure poses risks of kidney and liver damage, difficulty breathing, and asthma-like symptoms. Notably, cities with elevated PAH levels may witness exacerbation of bronchial asthma and chronic obstructive pulmonary disease (COPD). Bioremediation techniques utilising microorganisms emerge as a promising avenue to mitigate PAH-related health risks by facilitating the breakdown of these compounds in polluted environments. Furthermore, this review delves into the global concern of antimicrobial resistance associated with PAHs, highlighting its implications. The environmental effects and applications of genetically altered microbes in addressing this challenge warrant further exploration, emphasising the dynamic nature of ongoing research in this field. © 2024 Elsevier Ltd
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Biodegradation, Environmental; Cities; Environmental Monitoring; Humans; Polycyclic Aromatic Hydrocarbons; Soil; Soil Pollutants; polycyclic aromatic hydrocarbon; bioremediation; city; environmental monitoring; human; procedures; soil; soil pollutant |
| Subjects: | Q Science > QR Microbiology R Medicine > RA Public aspects of medicine R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Faculty of Medicine > Department of Molecular Medicine Faculty of Medicine > Medical Microbiology Department Faculty of Medicine > Physiology Department Faculty of Science > Institute of Biological Sciences Faculty of Pharmacy > Department of Pharmaceutical Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 09 Jul 2024 08:57 |
| Last Modified: | 09 Jul 2024 08:57 |
| URI: | http://eprints.um.edu.my/id/eprint/44731 |
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