Lam, Sai Kit; Chua, Kaw Bing (2002) Nipah virus encephalitis outbreak in Malaysia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 34 Sup. S48-51. ISSN 1537-6591Full text not available from this repository.
Emerging infectious diseases involving zoonosis have become important global health problems. The 1998 outbreak of severe febrile encephalitis among pig farmers in Malaysia caused by a newly emergent paramyxovirus, Nipah virus, is a good example. This disease has the potential to spread to other countries through infected animals and can cause considerable economic loss. The clinical presentation includes segmental myoclonus, areflexia, hypertension, and tachycardia, and histologic evidence includes endothelial damage and vasculitis of the brain and other major organs. Magnetic resonance imaging has demonstrated the presence of discrete high-signal-intensity lesions disseminated throughout the brain. Nipah virus causes syncytial formation in Vero cells and is antigenically related to Hendra virus. The Island flying fox (Pteropus hypomelanus; the fruit bat) is a likely reservoir of this virus. The outbreak in Malaysia was controlled through the culling of >1 million pigs.
|Journal or Publication Title:||Clinical infectious diseases : an official publication of the Infectious Diseases Society of America|
|Uncontrolled Keywords:||Animals; Cercopithecus aethiops; Chiroptera/virology; Encephalitis/pathology;|
|Subjects:||R Medicine > R Medicine (General)|
R Medicine > RB Pathology
|Divisions:||Faculty of Medicine|
|Depositing User:||Mr. Faizal Hamzah|
|Date Deposited:||10 Mar 2011 09:09|
|Last Modified:||10 Mar 2011 09:09|
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