Ong, Sok King and Haruyama, Rei and Yip, Cheng Har and Ngan, Tran Thu and Li, Jingmei and Lai, Daphne and Zhang, Yawei and Yi, Siyan and Shankar, Abhishek and Suzanna, Evlina and Jung, So-Youn and Ho, Peh Joo and Yusuf, Aasim and Nessa, Ashrafun and Jung, Kyu-Won and Fernando, Eshani and Baral, Shweta and Bagherian, Maryam and Pradhan, Prabhat and Jugder, Uranbolor and Vongdala, Champadeng and Yusof, Siti Norbayah and Thiri, Khin and Sripan, Patumrat and Cairo, Clarito and Matsuda, Tomohiro and Sangrajran, Suleeporn and Tan, Veronique Kiak-Mien and Mehrotra, Ravi and Anderson, Benjamin O. (2024) Feasibility of monitoring Global Breast Cancer Initiative Framework key performance indicators in 21 Asian National Cancer Centers Alliance member countries. ECLINICALMEDICINE, 67. ISSN 2589-5370, DOI https://doi.org/10.1016/j.eclinm.2023.102365.
Full text not available from this repository.Abstract
Bckground The Global Breast Cancer Initiative (GBCI) Framework, launched by the World Health Organisation (WHO) in 2023, emphasises assessing, strengthening, and scaling up services for the early detection and management of breast cancer. This study aims to determine the feasibility of monitoring the status of breast cancer control in the 21 Asian National Cancer Centers Alliance (ANCCA) countries based on the three GBCI Framework key performance indicators (KPIs): stage at diagnosis, time to diagnosis, and treatment completion.Methods We reviewed published literature on breast cancer control among 21 ANCCA countries from May to July 2023 to establish data availability and compiled the latest descriptive statistics and sources of the indicators using a standardised data collection form. We performed bivariate Pearson's correlation analysis to measure the strength of correlation between stage at diagnosis, mortality and survival rates, and universal health coverage.Findings Only 12 (57%) ANCCA member countries published national cancer registry reports on breast cancer age -standardised incidence rate (ASIR) and age-standardised mortality rate (ASMR). Indonesia, Myanmar, and Nepal had provincial data and others relied on WHO's Global Cancer Observatory (GLOBOCAN) estimates. GLOBOCAN data differed from the reported national statistics by 5-10% in Bhutan, Indonesia, Iran, the Republic of Korea, Singapore, and Thailand and >10% in China, India, Malaysia, Mongolia, and Sri Lanka. The proportion of patients diagnosed in stages I and II strongly correlated with the five-year survival rate and with the universal health coverage (UHC) index. Three countries (14%) reported national data with >60% of invasive breast cancer patients diagnosed at stages I and II, and a five-year survival rate of >80%. Over 60% of the ANCCA countries had no published national data on breast cancer staging, the time interval from presentation to diagnosis, and diagnosis to treatment. Five (24%) countries reported data on treatment completion. The definition of delayed diagnosis and treatment completion varied across countries. Interpretation GBCI's Pillar 1 KPI correlates strongly with five-year survival rate and with the UHC index. Most ANCCA countries lacked national data on cancer staging, timely diagnosis, and treatment completion KPIs. While institutional-level data were available in some countries, they may not represent the nationwide status. Strengthening cancer surveillance is crucial for effective breast cancer control. The GBCI Framework indicators warrant more detailed definitions for standardised data collection. Surrogate indicators which are measurable and manageable in country-specific settings, could be considered for monitoring GBCI indicators. Ensuring UHC and addressing health inequalities are essential to early diagnosis and treatment of breast cancer.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Breast cancer; WHO GBCI Framework; Feasibility; Indicators; Cancer stage; Survival; Screening; Early diagnosis; Completion of treatment; ANCCA; Asia |
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Faculty of Medicine > Surgery Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 26 Jun 2024 08:08 |
| Last Modified: | 26 Jun 2024 08:08 |
| URI: | http://eprints.um.edu.my/id/eprint/44235 |
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