Loo, Wai Yang and Tee, Ying Chew and Han, Winn Hui and Faheem, Nik Aimee Azizah and Yong, Shin Shen and Kwan, Zhenli and Pok, Lydia Say Lee and Yahya, Fariz (2024) Predictive factors of psoriatic arthritis in a diverse population with psoriasis. Journal of International Medical Research, 52 (1). ISSN 0300-0605, DOI https://doi.org/10.1177/03000605231221014.
Full text not available from this repository.Abstract
Objective: We aimed to analyze the clinical characteristics of patients with psoriasis and determine the predictive factors of psoriatic arthritis (PsA). Methods: This retrospective cohort study was performed among patients with psoriasis. Demographic and clinical data were collected. Psoriasis treatment was categorized as topical agents, phototherapy, oral therapy, and biologics. Predictive factors of PsA development were determined using logistic regression analyses.ResultsWe included 330 patients with psoriasis, and 83 (25%) patients developed PsA. Thirty-eight (45.8%) patients who developed PsA were Malay, 24 (28.9%) were Chinese, and 21 (25.3%) were Indian. The mean age of patients with PsA was 54.2 (+/- 15.8) years, and the duration from diagnosis of psoriasis to diagnosis of PsA was 36 (3.5-114) months. Predictive factors for developing PsA were female sex (odds ratio OR] = 3.33, 95% confidence interval CI] 1.78-6.22), presence of nail involvement (OR = 5.36, 95% CI 2.50-11.51), severe psoriasis (OR = 27.41, 95% CI 7.58-99.11), and oral systemic therapy prior to PsA diagnosis (OR = 4.09, 95% CI 2.04-8.22). Conclusion: Patients with psoriasis who are female, have nail involvement, have severe skin psoriasis, and require oral systemic therapy for psoriasis may have an increased risk of developing PsA.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Predictive factor; psoriatic arthritis; psoriasis; prediction; retrospective cohort study; risk factor |
| Subjects: | R Medicine > RL Dermatology |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 20 Jun 2024 01:58 |
| Last Modified: | 20 Jun 2024 01:58 |
| URI: | http://eprints.um.edu.my/id/eprint/44199 |
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