Goh, Wei Jan and Chan, Bee Ting and Ab Naim, Wan Naimah Wan and Chuah, Shoon Hui and Lim, Einly and Liew, Yih Miin (2022) Wall stress analysis of patient-specific left ventricular hypertrophy models. In: 6th Kuala Lumpur International Conference on Biomedical Engineering, BioMed 2021, 28-29 July 2021, Virtual, Online.
Full text not available from this repository.Abstract
Left ventricular hypertrophy (LVH) is a complex heart disease characterised by abnormal heart wall. A wall stress analysis may provide insight on ventricular wall mechanics, and it should be conducted with patient-specific geometry for accurate assessment. This study aims to investigate the distribution of stress on the left ventricular (LV) wall of LVH patients in diastolic filling phase using the finite element method. The patient-specific LV geometries of two LVH patients were compared with two healthy subjects. The effect of individual factors in contributing to wall stress was also studied by adapting the model settings for investigation. Our results showed that the excessive wall stress observed in LVH patients (σc: 6068±342Pa, σz: 3785±161Pa, σr: 384±649Pa ), when compared to healthy subjects (σc: 2662±82Pa, σz: 1486±239Pa, σr: 0.1±47Pa ), were mainly contributed by the elevated filling pressure. Besides, an abnormal stress variation was also observed in LVH patients, especially near the region with wall thickening and distinct local wall curvature. A high convexity area was observed to have high circumferential stress and low longitudinal stress, while the opposite was noted at the local high concavity area. These findings indicate the importance of patient-specific models in wall stress assessment of LVH patients. © 2022, Springer Nature Switzerland AG.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Funders: | Universiti Malaya [Grant no. GPF053B-2020], University of Nottingham Malaysia Campus |
| Uncontrolled Keywords: | Cardiology; Stress analysis; Healthy subjects; Heart disease; Heart wall; Left ventricular; Left ventricular hypertrophies; Patient specific; Stresses analysis; Ventricular walls; Wall mechanics; Wall Stress; Pathology |
| Subjects: | R Medicine T Technology > TJ Mechanical engineering and machinery |
| Divisions: | Faculty of Engineering > Biomedical Engineering Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 12 Feb 2025 03:35 |
| Last Modified: | 12 Feb 2025 03:35 |
| URI: | http://eprints.um.edu.my/id/eprint/43479 |
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