Subacute myelopathy following intrathecal chemotherapy administration

Mumin, N Ab and Hamid, MT Ramli and Rahmat, Kartini and Jawin, V. and Mohd Ramli, Norlisah (2022) Subacute myelopathy following intrathecal chemotherapy administration. Brunei International Medical Journal, 2022 (18). 29 – 33. ISSN 1560-5876,

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Abstract

Methotrexate and cytarabine are intrathecal chemotherapy agents for acute lymphoblastic leukaemia. We report a case of a paediatric patient with late onset CNS relapse of Pre-B acute lymphoblastic leukaemia who developed chemotherapy-induced myelopathy secondary to triple intrathecal chemotherapy (TIT) with its imaging findings. Imaging plays a role in localising abnormality within the spinal cord for diagnosis and aids clinicians to prevent further axonal damage by stopping the causative chemotherapeutic agents. © 2022, Brunei International Medical Journal. All rights reserved.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Acute lymphoblastic leukemia; Chemotherapy-induced; Intrathecal; Magnetic resonance imaging; Myelopathy
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Biomedical Imaging Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 10 Feb 2025 03:57
Last Modified: 10 Feb 2025 03:57
URI: http://eprints.um.edu.my/id/eprint/43301

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