A clinicopathological and immunohistochemical study of the calcifying epithelial odontogenic tumour (Pindborg tumour) in Malaysians
Ng, K.H.; Siar, C.H. (1996) A clinicopathological and immunohistochemical study of the calcifying epithelial odontogenic tumour (Pindborg tumour) in Malaysians. Journal of Laryngology and Otology, 110 (8). pp. 757-762. ISSN 0022-2151
We reviewed the clinicopathological characteristics of 13 cases of calcifying epithelial odontogenic tumour (CEOT) (Pindborg tumour) diagnosed in the Division on Stomatology, Institute for Medical Research, Kuala Lumpur, over a 29-year period. There were eight female and five male patients. These consisted of eight (61.5 per cent) Malays, three (23.1 per cent) Chinese, one (7.7 per cent) Indian and one (7.7 per cent) Melanau. Their ages at presentation ranged from 19-61 years (mean age, 31.8 years). There were 12 central and one peripheral CEOT. Of these, 76.9 per cent of cases were located in the maxilla, the remaining in the mandible. The commonest clinical diagnosis was a dentigerous cyst (66.7 per cent). Enucleation was the main mode of treatment. Histologically, sheets and strands of polyhedral epithelial cells containing eosinophilic, homogeneous globules with Liesegang rings were observed. One case also showed extensive calcification and clear cell differentiation. Immunohistochemistry revealed a variable keratin staining of the CEOT epithelium, confirming its heterogeneity.
|Item Type: ||Article|
- Ng, K.H.
- Siar, C.H.
|Journal or Publication Title: ||Journal of Laryngology and Otology|
|Additional Information: ||ISI Document Delivery No.: VD250 Times Cited: 9 Cited Reference Count: 26 Cited References: AI-RU L, 1982, Journal of Oral Pathology, V11, P399, DOI 10.1111/j.1600-0714.1982.tb00181.x ANDRADE M, 1992, J ORAL MAXIL SURG, V50, P1324, DOI 10.1016/0278-2391(92)90236-S ASANO M, 1990, J ORAL PATHOL MED, V19, P430, DOI 10.1111/j.1600-0714.1990.tb00874.x BAUNSGAARD P, 1983, LARYNGOSCOPE, V93, P635 DAMM DD, 1983, ORAL SURG ORAL MED O, V55, P487, DOI 10.1016/0030-4220(83)90235-9 ELLABBAN NG, 1990, J ORAL PATHOL MED, V19, P166 FRANKLIN CD, 1976, BRIT J ORAL SURG, V13, P230, DOI 10.1016/0007-117X(76)90050-0 FRANKLIN CD, 1976, ORAL SURG ORAL MED O, V42, P753, DOI 10.1016/0030-4220(76)90098-0 GREER RO, 1976, ORAL SURG ORAL MED O, V42, P775, DOI 10.1016/0030-4220(76)90100-6 Kramer I, 1992, Histological typing of odontogenic tumors, P7 KROLLS SO, 1974, ARCH PATHOL, V98, P206 LEE CYS, 1992, J ORAL MAXIL SURG, V50, P1326, DOI 10.1016/0278-2391(92)90237-T LEIPZIG B, 1982, OTOLARYNG HEAD NECK, V90, P69 MORI M, 1988, J ORAL PATHOL MED, V17, P236, DOI 10.1111/j.1600-0714.1988.tb01531.x OIKARINEN VJ, 1976, INT J ORAL MAXILLOF, V5, P187, DOI 10.1016/S0300-9785(76)80043-9 PATTERSO.JT, 1969, ORAL SURG ORAL MED O, V27, P363, DOI 10.1016/0030-4220(69)90367-3 PINDBORG JJ, 1955, ACTA PATHOLOGICA M S, V11, P71 RICHARDS.JF, 1974, CANCER, V34, P1244, DOI 10.1002/1097-0142(197410)34:4<1244::AID-CNCR2820340434>3.0.CO;2-J SIAR CH, 1991, BRIT J ORAL MAX SURG, V29, P106, DOI 10.1016/0266-4356(91)90093-K Siar C H, 1987, Singapore Med J, V28, P180 SIAR CH, 1987, INT J ORAL MAX SURG, V16, P214 SLOOTWEG PJ, 1991, J ORAL PATHOL MED, V20, P93, DOI 10.1111/j.1600-0714.1991.tb00897.x TAKATA T, 1993, J ORAL PATHOL MED, V22, P378, DOI 10.1111/j.1600-0714.1993.tb01093.x TAKEDA Y, 1983, ORAL SURG ORAL MED O, V56, P71, DOI 10.1016/0030-4220(83)90058-0 VAP DR, 1970, CANCER, V25, P629, DOI 10.1002/1097-0142(197003)25:3<629::AID-CNCR2820250319>3.0.CO;2-H WALLACE J, 1974, BRIT J PLAST SURG, V27, P28, DOI 10.1016/0007-1226(74)90057-5 Ng, KH Siar, CH Headley brothers ltd Ashford|
|Uncontrolled Keywords: ||Jaw neoplasms odontogenic tumours langerhans cells cementum Jaw neoplasms Odontogenic tumours adult article calcification cell differentiation clinical article clinical feature enucleation eosinophil epithelium cell epithelium tumor female human malaysia male mandible tumor maxilla tumor odontogenic tumor teratoma Humans Immunohistochemistry Keratins Maxillary Neoplasms Middle Aged Odontogenic Cyst, Calcifying Tumor Markers, Biological|
|Subjects: ||R Medicine > RK Dentistry|
|Divisions: ||Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology|
|Depositing User: ||Ms Nursyafiqah Abd Malek|
|Date Deposited: ||10 Jan 2013 08:07|
|Last Modified: ||10 Jan 2013 08:07|
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