Priorities for cancer research in low- and middle-income countries: a global perspective

Pramesh, C. S. and Badwe, Rajendra A. and Bhoo-Pathy, Nirmala and Booth, Christopher M. and Chinnaswamy, Girish and Dare, Anna J. and de Andrade, Victor Piana and Hunter, David J. and Gopal, Satish and Gospodarowicz, Mary and Gunasekera, Sanjeeva and Ilbawi, Andre and Kapambwe, Sharon and Kingham, Peter and Kutluk, Tezer and Lamichhane, Nirmal and Mutebi, Miriam and Orem, Jackson and Parham, Groesbeck and Ranganathan, Priya and Sengar, Manju and Sullivan, Richard and Swaminathan, Soumya and Tannock, Ian F. and Tomar, Vivek and Vanderpuye, Verna and Varghese, Cherian and Weiderpass, Elisabete (2022) Priorities for cancer research in low- and middle-income countries: a global perspective. Nature Medicine, 28 (4). pp. 649-657. ISSN 1078-8956, DOI https://doi.org/10.1038/s41591-022-01738-x.

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Abstract

Radical rethinking is needed to address the burning issues in cancer care in low- and middle-income countries. In this Perspective, the authors outline the main challenges and top priorities for cancer research now and into the future. Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional discordance in cancer knowledge generation and application needs to be rebalanced. Several gaps in the research enterprise of LMICs need to be addressed to promote regionally relevant research, and radical rethinking is needed to address the burning issues in cancer care in these regions. We identified five top priorities in cancer research in LMICs based on current and projected needs: reducing the burden of patients with advanced disease; improving access and affordability, and outcomes of cancer treatment; value-based care and health economics; quality improvement and implementation research; and leveraging technology to improve cancer control. LMICs have an excellent opportunity to address important questions in cancer research that could impact cancer control globally. Success will require collaboration and commitment from governments, policy makers, funding agencies, health care organizations and leaders, researchers and the public.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Cancer; Research; Low--income countries; Middle-income countries
Subjects: R Medicine
Divisions: Faculty of Medicine > Social & Preventive Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 11 Sep 2023 07:45
Last Modified: 11 Sep 2023 07:45
URI: http://eprints.um.edu.my/id/eprint/42934

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