Regenerative medicine therapy in Malaysia: An update

Imran, Siti A. M. and Hamizul, M. Haikal Aiman M. and Bariah, Ahmad Amin Noordin Khairul and Wan Kamarul Zaman, Wan Safwani and Nordin, Fazlina (2022) Regenerative medicine therapy in Malaysia: An update. Frontiers in Bioengineering And Biotechnology, 10. ISSN 2296-4185, DOI https://doi.org/10.3389/fbioe.2022.789644.

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Abstract

Regenerative medicine is a field in medicine that relates to the ability to correct congenital anomalies and to repair or replace tissues and organs that have been destroyed by age, disease, or trauma. To date, promising preclinical and clinical data supported the possibility of using regenerative medicine to treat both chronic diseases and acute insults, as well as maladies affecting a wide range of organ systems and contexts, such as dermal wounds, cardiovascular diseases and traumas, cancer treatments, and more. One of the regenerative medicine therapies that have been used widely is stem cells. Stem cells, especially mesenchymal and hematopoietic stem cells, play an important role in treating chronic diseases, such as leukemia, bone marrow, autoimmune disease, and urinary problems. Despite considerable advancements in stem cell biology, their applications are limited by ethical concerns about embryonic stem cells, tumor development, and rejection. Nevertheless, many of these constraints, are being overcome, which could lead to significant advancements in disease management. This review discusses the current developments and advancements of regenerative medicine therapy (RMT) advancements in Malaysia compared to other Asian countries. The limitations in the application of RMT are also highlighted.

Item Type: Article
Funders: Universiti Kebangsaan Malaysia through the Faculty of Medicine grant (FF-2021-378)
Uncontrolled Keywords: Regenerative medicine therapy; cell therapy; Stem cells; Tissue engineering; Biomaterials; Clinical trials; Malaysia; Asia
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
R Medicine
T Technology > T Technology (General)
Divisions: Faculty of Engineering > Biomedical Engineering Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 29 Aug 2023 07:06
Last Modified: 29 Aug 2023 07:06
URI: http://eprints.um.edu.my/id/eprint/42867

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