Tan, Rachel Yie Hang and Lee, Choy Sin and Pichika, Mallikarjuna Rao and Cheng, Sit Foon and Lam, Ki Yan (2022) PH responsive polyurethane for the advancement of biomedical and drug delivery. Polymers, 14 (9). ISSN 2073-4360, DOI https://doi.org/10.3390/polym14091672.
Full text not available from this repository.Abstract
Due to the specific physiological pH throughout the human body, pH-responsive polymers have been considered for aiding drug delivery systems. Depending on the surrounding pH conditions, the polymers can undergo swelling or contraction behaviors, and a degradation mechanism can release incorporated substances. Additionally, polyurethane, a highly versatile polymer, has been reported for its biocompatibility properties, in which it demonstrates good biological response and sustainability in biomedical applications. In this review, we focus on summarizing the applications of pH-responsive polyurethane in the biomedical and drug delivery fields in recent years. In recent studies, there have been great developments in pH-responsive polyurethanes used as controlled drug delivery systems for oral administration, intravaginal administration, and targeted drug delivery systems for chemotherapy treatment. Other applications such as surface biomaterials, sensors, and optical imaging probes are also discussed in this review.
| Item Type: | Article |
|---|---|
| Funders: | Malaysian Ministry of Higher Education [Grant No: FRGS/1/2019/STG07/IMU/02/1], Malaysia Ministry of Higher Education, Fundamental Research Grant Scheme (FRGS) [Grant No: FRGS/1/2019/STG07/IMU/02/1] |
| Uncontrolled Keywords: | pH-responsive; Polyurethane; Biomedical; Drug delivery |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 29 Sep 2023 08:44 |
| Last Modified: | 27 Nov 2024 03:42 |
| URI: | http://eprints.um.edu.my/id/eprint/42857 |
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