Rafique Ali, Abdullah Ashraf and Ismail, Fazliana and May May, Choo and Mohd Abdullah, Azlindarita Aisyah and Khaliddin, Nurliza and Hariri, Firdaus and Abdul Rahman, Zainal Ariff and Mohamed Iqbal, Tajunisah Begam (2022) Ophthalmic features of craniosynostosis: A Malaysian experience. European Journal of Ophthalmology, 32 (3). pp. 1417-1423. ISSN 1120-6721, DOI https://doi.org/10.1177/11206721211030093.
Full text not available from this repository.Abstract
Background: This study aims to collect local Malaysian data regarding the ophthalmic features and complications in craniosynostosis patients who attended the Combined Craniofacial Clinic (CFC) in University Malaya Medical Centre (UMMC). Methods: Retrospective study of medical notes of craniosynostosis patients who attended the CFC in UMMC from 2014 to December 2020. Results: Out of 37 patients, 29 had syndromic craniosynostosis, and 8 had non-syndromic craniosynostosis. Visual impairment was present in 32.1% of patients. Causes for visual impairment were as follows - amblyopia (25.0%), exposure keratopathy (3.6%), and optic atrophy (3.6%). Hypermetropia and myopia were each seen in 20.6% of patients. Astigmatism was seen in 47.1% of patients, and 29.1% had anisometropia. Proptosis was present in 78.6% and lagophthalmos in 53.3% of patients. Strabismus in primary position occurred in 51.7% of patients. Thirty-one percent of the patients had exposure keratopathy. Optic disc atrophy was seen in 13.7% of patients, and 8.3% had optic disc swelling. Optic disc swelling was resolved in all patients who underwent craniofacial surgery. Conclusion: Our experience in Malaysia was consistent with previously reported data on ophthalmic features of craniosynostosis patients. Additionally, we found that non-syndromic craniosynostosis patients are also at risk of ocular complications just as much as syndromic patients. Appropriate treatment of amblyogenic risk factors, ocular complications, and timely detection of papilledema, and prompt surgical intervention are crucial in preserving long-term visual function in these patients.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Craniosynostosis; Apert; Pfeiffer; Crouzon; Ophthalmic features; Visual impairment; Amblyopia; Strabismus |
| Subjects: | R Medicine > RE Ophthalmology |
| Divisions: | Faculty of Dentistry Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 07 Oct 2023 04:43 |
| Last Modified: | 07 Oct 2023 04:43 |
| URI: | http://eprints.um.edu.my/id/eprint/42446 |
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