Carboxylated nanocellulose dispersed nitrogen doped graphene nanosheets and sodium dodecyl sulfate modified electrochemical sensor for the simultaneous determination of paracetamol and naproxen sodium

Shalauddin, Md and Akhter, Shamima and Basirun, Wan Jefrey and Anuar, Nadzirah Sofia and Akbarzadeh, Omid and Mohammed, Mohammed Alhaji and Johan, Mohammad Rafie (2022) Carboxylated nanocellulose dispersed nitrogen doped graphene nanosheets and sodium dodecyl sulfate modified electrochemical sensor for the simultaneous determination of paracetamol and naproxen sodium. Measurement, 194. ISSN 0263-2241, DOI https://doi.org/10.1016/j.measurement.2022.110961.

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Abstract

An innovative electrochemical sensing platform was fabricated for the simultaneous determination of paracetamol (PCT) and naproxen sodium (NPX). The glassy carbon electrode (GCE) was modified with a hybrid porous nanocomposite of carboxylated nanocellulose (CNCS), nitrogen doped graphene (NDG) and an anionic surfactant sodium dodecyl sulfate (SDS) by simple ultrasonication and drop-casting method. The (CNCS-NDG)-SDS nanocomposite showed high electrocatalytic performance towards the redox reaction of PCT and the oxidation of NPX between 0.2 V and 0.9 V at 0.1 V s- 1 with broad linear ranges from 0.01 to 90 mu M and 0.1 to 60 mu M for PCT and NPX, respectively. The limit of detection is 0.0015 mu M and 0.0018 mu M for PCT and NPX, respectively, while the limit of quantification is 0.015 mu M and 0.018 mu M, respectively. The (CNCS-NDG)-SDS/GCE sensor showed good stability, reproducibility and repeatability for the electrochemical determination of PCT and NPX.

Item Type: Article
Funders: University Malaya Kuala Lumpur, Ministry of Higher Education (MOHE) Malaysia [Grant No; IIRG010B-2019, RU001-2020], Federal Government of Nigeria, Management of Federal University of Lafia
Uncontrolled Keywords: Electrochemical sensor; TEMPO; Carboxylated-nanocellulose; Nitrogen doped graphene; Sodium dodecyl sulfate
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science > Department of Chemistry
Nanotechnology & Catalysis Research Centre
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 12 Oct 2023 07:38
Last Modified: 12 Oct 2023 07:38
URI: http://eprints.um.edu.my/id/eprint/42322

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