Rozaini, Muhammad Nur' Hafiz and Saad, Bahruddin and Lim, Jun Wei and Yahaya, Noorfatimah and Ramachandran, Muggundha Raoov and Kiatkittipong, Worapon and Mohamad, Mardawani and Chan, Yi Jing and Goh, Pei Sean and Shaharun, Maizatul Shima (2022) Development of ?-cyclodextrin crosslinked citric acid encapsulated in polypropylene membrane protected-?-solid-phase extraction device for enhancing the separation and preconcentration of endocrine disruptor compounds. Chemosphere, 303 (1). ISSN 0045-6535, DOI https://doi.org/10.1016/j.chemosphere.2022.135075.
Full text not available from this repository.Abstract
Endocrine disruptor compounds (EDCs) such as plasticisers, surfactants, pharmaceutical products, personal care products and pesticides are frequently released into the environmental waters. Therefore, a sensitive and environmentally friendly method is entailed to quantify these compounds at their trace level concentrations. This study encapsulated the 13-cyclodextrin crosslinked with citric acid in a polypropylene membrane protected mu-solid phase extraction (BCD-CA mu-SPE) device for preconcentrating the EDCs (triclosan, triclocarban, 2 phenylphenol, 4-tert-octylphenols and bisphenol A) in real water samples before the analysis by high-performance liquid chromatography. FT-IR and TGA results indicated that BCD-CA was successfully syn-thesised with the formation of ester linkage (1078.33 cm-1) and O-H stretching from carboxylic acid (3434.70 cm-1) with higher thermal stability as compared with native CD with the remaining weight above 72.1% at 500 degrees C. Several critical parameters such as the sorbent loading, type and amount of salts, extraction time, sample volume, sample pH, type and volume of desorption solvents and desorption time were sequentially optimised and statistically validated. Under the optimum condition, the use of BCD-CA mu-SPE device had manifested good linearity (0.5-500 mu g L-1) with the determination of the coefficient range of 0.9807-0.9979. The p-values for the F-test and t-test (6.60 x 10-8 - 1.77 x 10-5) were lesser than 0.05 and low detection limits ranging from 0.27 to 0.84 mu g L-1 for all studied EDCs. The developed technique was also successfully applied for EDC analyses in four distinct real water samples, namely, wastewater, river water, tap water and mineral water, with good EDCs recoveries (80.2%-99.9%), low relative standard deviations (0.1%-3.8%, n = 3) with enrichment factor ranging from 9 to 82 folds. These results signified the potential of the BCD-CA mu-SPE device as an efficient, sensitive, and environmentally friendly approach for analyzing EDCs.
| Item Type: | Article |
|---|---|
| Funders: | Yayasan Universiti Tekno-logi PETRONAS [Grant No; YUTP-015LC0-211] |
| Uncontrolled Keywords: | Beta-cyclodextrin crosslinked with citric acid; Polypropylene membrane; Solid-phase extraction; Endocrine disruptor compound; Environmental water |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 13 Oct 2023 08:16 |
| Last Modified: | 13 Oct 2023 08:16 |
| URI: | http://eprints.um.edu.my/id/eprint/42162 |
Actions (login required)
 |
View Item |
